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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDH5
All Species:
15.15
Human Site:
T221
Identified Species:
30.3
UniProt:
Q92781
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92781
NP_002896.2
318
34979
T221
N
L
E
S
L
E
K
T
L
Q
A
C
W
A
R
Chimpanzee
Pan troglodytes
XP_522429
318
34973
T221
N
L
E
S
L
E
K
T
L
Q
A
C
W
A
R
Rhesus Macaque
Macaca mulatta
XP_001110917
318
34857
T221
N
L
E
S
L
E
K
T
L
Q
A
C
W
A
R
Dog
Lupus familis
XP_538220
339
37270
T242
N
L
E
H
L
E
N
T
L
Q
E
C
W
A
R
Cat
Felis silvestris
Mouse
Mus musculus
O88451
316
35642
S221
N
Y
E
R
L
S
H
S
I
E
K
L
W
D
Q
Rat
Rattus norvegicus
P50170
317
35579
N222
N
G
V
T
L
S
S
N
F
Q
M
L
W
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508932
322
35450
A225
S
L
P
S
L
E
G
A
L
R
E
R
W
D
R
Chicken
Gallus gallus
Q5ZJZ5
339
38218
M193
V
V
N
I
S
S
M
M
G
R
M
G
S
P
A
Frog
Xenopus laevis
Q0IH28
323
35135
A197
A
Y
S
A
S
K
H
A
T
Q
A
F
F
D
C
Zebra Danio
Brachydanio rerio
NP_001025272
328
36748
E232
S
L
E
P
I
E
R
E
L
H
R
L
W
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
A212
A
Y
S
A
S
K
H
A
M
Q
A
F
A
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
F173
S
I
Y
C
A
S
K
F
A
V
G
A
F
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.4
84.9
N.A.
51.5
52.2
N.A.
67
33.6
25.3
52.7
N.A.
24.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.3
90.2
N.A.
70.4
70.4
N.A.
81
49.2
42.4
69.5
N.A.
42.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
26.6
26.6
N.A.
46.6
0
13.3
33.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
53.3
40
N.A.
60
13.3
33.3
60
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
17
9
0
0
25
9
0
42
9
9
34
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
34
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
9
% D
% Glu:
0
0
50
0
0
50
0
9
0
9
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
9
0
0
17
17
0
0
% F
% Gly:
0
9
0
0
0
0
9
0
9
0
9
9
0
0
0
% G
% His:
0
0
0
9
0
0
25
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
9
9
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
17
34
0
0
0
9
0
0
0
0
% K
% Leu:
0
50
0
0
59
0
0
0
50
0
0
25
0
0
0
% L
% Met:
0
0
0
0
0
0
9
9
9
0
17
0
0
0
0
% M
% Asn:
50
0
9
0
0
0
9
9
0
0
0
0
0
9
0
% N
% Pro:
0
0
9
9
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
59
0
0
0
0
25
% Q
% Arg:
0
0
0
9
0
0
9
0
0
17
9
9
0
0
42
% R
% Ser:
25
0
17
34
25
34
9
9
0
0
0
0
9
0
9
% S
% Thr:
0
0
0
9
0
0
0
34
9
0
0
0
0
9
0
% T
% Val:
9
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% W
% Tyr:
0
25
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _