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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RDH5 All Species: 25.76
Human Site: T273 Identified Species: 51.52
UniProt: Q92781 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92781 NP_002896.2 318 34979 T273 R C L E H A L T A R H P R T R
Chimpanzee Pan troglodytes XP_522429 318 34973 T273 R C L E H A L T A R H P R T R
Rhesus Macaque Macaca mulatta XP_001110917 318 34857 T273 Q C L E H A L T A R H P R T R
Dog Lupus familis XP_538220 339 37270 T294 R C L E H A L T A R Y P R T R
Cat Felis silvestris
Mouse Mus musculus O88451 316 35642 T272 D C M E H A L T A C H P R T R
Rat Rattus norvegicus P50170 317 35579 T273 D C M E H A L T S C H P R T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508932 322 35450 T277 N C L E H A L T A R H P R T R
Chicken Gallus gallus Q5ZJZ5 339 38218 P261 D K M W D E L P E I V R K D Y
Frog Xenopus laevis Q0IH28 323 35135 V260 P E E V A Q T V L R A V G E R
Zebra Danio Brachydanio rerio NP_001025272 328 36748 L284 N C M E H A L L A V H P R T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y140 326 35725 R274 S P D K L A E R I L Q C I L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05016 267 29140 D223 Q A K N V Y K D T T P L M A D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.4 84.9 N.A. 51.5 52.2 N.A. 67 33.6 25.3 52.7 N.A. 24.2 N.A. N.A. N.A.
Protein Similarity: 100 99.6 99.3 90.2 N.A. 70.4 70.4 N.A. 81 49.2 42.4 69.5 N.A. 42.9 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 80 73.3 N.A. 93.3 6.6 13.3 73.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 93.3 20 13.3 80 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 75 0 0 59 0 9 0 0 9 0 % A
% Cys: 0 67 0 0 0 0 0 0 0 17 0 9 0 0 0 % C
% Asp: 25 0 9 0 9 0 0 9 0 0 0 0 0 9 9 % D
% Glu: 0 9 9 67 0 9 9 0 9 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 67 0 0 0 0 0 59 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 9 0 0 9 0 0 % I
% Lys: 0 9 9 9 0 0 9 0 0 0 0 0 9 0 0 % K
% Leu: 0 0 42 0 9 0 75 9 9 9 0 9 0 9 0 % L
% Met: 0 0 34 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 17 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 9 0 0 0 0 0 9 0 0 9 67 0 0 0 % P
% Gln: 17 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % Q
% Arg: 25 0 0 0 0 0 0 9 0 50 0 9 67 0 84 % R
% Ser: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 59 9 9 0 0 0 67 0 % T
% Val: 0 0 0 9 9 0 0 9 0 9 9 9 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _