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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STAM All Species: 20.61
Human Site: S191 Identified Species: 30.22
UniProt: Q92783 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92783 NP_003464.1 540 59180 S191 L K E Q R Q Q S T T L S T L Y
Chimpanzee Pan troglodytes XP_001153098 540 59188 S191 L K E Q R Q Q S T T L S T L Y
Rhesus Macaque Macaca mulatta XP_001094352 504 55291 R180 Q H E G R K V R A I Y D F E A
Dog Lupus familis XP_535174 538 59187 S191 L K E Q R Q Q S T T L S T L Y
Cat Felis silvestris
Mouse Mus musculus P70297 548 59753 S191 L K E Q R Q Q S A P V S T L Y
Rat Rattus norvegicus Q5XHY7 523 57141 Q183 L S L Q E Q K Q Q Y P E T K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509197 529 57559 S189 L K E Q R Q Q S T T V S S L Y
Chicken Gallus gallus O93436 468 52388 S147 V T F P A A G S Q A T T N A A
Frog Xenopus laevis NP_001084997 459 50676 V140 K N L K E Q G V T F P A V G S
Zebra Danio Brachydanio rerio NP_956414 509 56319 H189 L S L K D Q R H Q Q P Q V S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477448 689 74616 S213 A Y P S L Y P S F A G T G S S
Honey Bee Apis mellifera XP_623539 539 59761 T199 S S H N S P S T K Y T S L Y P
Nematode Worm Caenorhab. elegans O01498 457 50811 K137 S L I V T L H K N L V A D G Y
Sea Urchin Strong. purpuratus XP_789926 606 64750 G193 S S Q S P S G G G G G G G G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38753 452 51142 L133 S L R A M G D L Y D K I K R K
Red Bread Mold Neurospora crassa Q7S6J4 745 78597 S219 A S G E G T N S T A G Q A E A
Conservation
Percent
Protein Identity: 100 99.8 92.4 95.7 N.A. 91 55.3 N.A. 84.2 52.4 72.2 70.7 N.A. 37.1 44.6 32.5 43.4
Protein Similarity: 100 100 92.7 97 N.A. 94.1 70.5 N.A. 89.2 65.5 78.1 79.4 N.A. 49.6 58.7 49.4 57.2
P-Site Identity: 100 100 13.3 100 N.A. 80 26.6 N.A. 86.6 6.6 13.3 13.3 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 100 20 100 N.A. 86.6 33.3 N.A. 100 20 26.6 26.6 N.A. 13.3 13.3 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.9 24.1
Protein Similarity: N.A. N.A. N.A. N.A. 42.2 37.7
P-Site Identity: N.A. N.A. N.A. N.A. 0 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 7 7 7 0 0 13 19 0 13 7 7 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 7 0 0 7 0 7 7 0 0 % D
% Glu: 0 0 38 7 13 0 0 0 0 0 0 7 0 13 0 % E
% Phe: 0 0 7 0 0 0 0 0 7 7 0 0 7 0 0 % F
% Gly: 0 0 7 7 7 7 19 7 7 7 19 7 13 19 7 % G
% His: 0 7 7 0 0 0 7 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 7 0 7 0 0 0 % I
% Lys: 7 32 0 13 0 7 7 7 7 0 7 0 7 7 7 % K
% Leu: 44 13 19 0 7 7 0 7 0 7 19 0 7 32 7 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 0 7 0 7 0 0 0 7 0 0 % N
% Pro: 0 0 7 7 7 7 7 0 0 7 19 0 0 0 7 % P
% Gln: 7 0 7 38 0 50 32 7 19 7 0 13 0 0 0 % Q
% Arg: 0 0 7 0 38 0 7 7 0 0 0 0 0 7 0 % R
% Ser: 25 32 0 13 7 7 7 50 0 0 0 38 7 13 13 % S
% Thr: 0 7 0 0 7 7 0 7 38 25 13 13 32 0 0 % T
% Val: 7 0 0 7 0 0 7 7 0 0 19 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 7 0 0 7 13 7 0 0 7 38 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _