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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX1
All Species:
27.88
Human Site:
S121
Identified Species:
51.11
UniProt:
Q92786
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92786
NP_002754.2
737
83203
S121
S
G
L
S
S
T
G
S
E
V
H
Q
E
D
I
Chimpanzee
Pan troglodytes
XP_522907
592
65532
A63
F
G
D
E
H
I
Q
A
K
R
A
R
V
E
T
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
A63
F
G
D
E
H
I
Q
A
K
R
A
R
V
E
T
Dog
Lupus familis
XP_858135
737
83203
S121
S
G
L
S
S
T
G
S
E
V
H
Q
E
D
I
Cat
Felis silvestris
Mouse
Mus musculus
P48437
737
83108
S121
S
G
L
S
S
T
G
S
E
V
H
Q
E
D
I
Rat
Rattus norvegicus
NP_001100671
583
64827
V54
P
Q
G
S
E
Q
D
V
E
Y
S
V
V
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511202
735
83058
S121
S
G
L
S
S
T
G
S
E
V
H
Q
E
D
V
Chicken
Gallus gallus
Q91018
736
83123
S121
S
G
L
S
S
T
G
S
E
V
H
Q
E
D
V
Frog
Xenopus laevis
NP_001084172
740
83918
S121
S
G
L
S
S
A
G
S
E
I
H
Q
E
D
A
Zebra Danio
Brachydanio rerio
NP_571480
739
83196
S121
S
G
L
S
S
T
G
S
E
M
Q
Q
E
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392355
1146
126812
T165
D
P
A
T
A
E
L
T
Q
H
M
L
R
D
I
Nematode Worm
Caenorhab. elegans
P34522
586
65798
R57
R
F
K
V
K
R
H
R
Q
R
V
D
A
G
E
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
G124
A
K
V
P
S
E
S
G
D
S
T
A
M
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
33.2
99.3
N.A.
98.3
77.6
N.A.
95.6
93.6
87.9
82.6
N.A.
N.A.
23.4
26.5
35
Protein Similarity:
100
46
46.5
99.5
N.A.
99.4
78.5
N.A.
98
96.1
93.7
89.3
N.A.
N.A.
36.9
45
51
P-Site Identity:
100
6.6
6.6
100
N.A.
100
13.3
N.A.
93.3
93.3
80
80
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
13.3
N.A.
100
100
86.6
86.6
N.A.
N.A.
40
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
0
16
0
0
16
8
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
0
0
8
0
8
0
0
8
0
62
0
% D
% Glu:
0
0
0
16
8
16
0
0
62
0
0
0
54
16
8
% E
% Phe:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
70
8
0
0
0
54
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
16
0
8
0
0
8
47
0
0
0
8
% H
% Ile:
0
0
0
0
0
16
0
0
0
8
0
0
0
0
31
% I
% Lys:
0
8
8
0
8
0
0
0
16
0
0
0
0
0
0
% K
% Leu:
0
0
54
0
0
0
8
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
8
16
0
16
0
8
54
0
8
0
% Q
% Arg:
8
0
0
0
0
8
0
8
0
24
0
16
8
0
0
% R
% Ser:
54
0
0
62
62
0
8
54
0
8
8
0
0
0
0
% S
% Thr:
0
0
0
8
0
47
0
8
0
0
8
0
0
0
24
% T
% Val:
0
0
8
8
0
0
0
8
0
39
8
8
24
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _