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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX1
All Species:
27.58
Human Site:
S142
Identified Species:
50.56
UniProt:
Q92786
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92786
NP_002754.2
737
83203
S142
D
S
P
P
E
C
L
S
P
F
G
R
P
T
M
Chimpanzee
Pan troglodytes
XP_522907
592
65532
P84
L
S
P
N
P
L
V
P
G
N
A
Q
A
G
V
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
P84
L
S
P
N
P
L
V
P
G
S
A
Q
A
G
D
Dog
Lupus familis
XP_858135
737
83203
S142
D
S
P
P
E
C
L
S
P
F
G
R
P
T
M
Cat
Felis silvestris
Mouse
Mus musculus
P48437
737
83108
S142
D
S
P
P
E
C
L
S
P
F
G
R
P
T
M
Rat
Rattus norvegicus
NP_001100671
583
64827
K75
N
V
L
R
K
L
L
K
R
A
N
S
Y
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511202
735
83058
S142
D
S
P
P
E
C
L
S
P
F
G
R
P
T
M
Chicken
Gallus gallus
Q91018
736
83123
S142
D
S
P
Q
E
C
L
S
P
F
G
R
P
T
M
Frog
Xenopus laevis
NP_001084172
740
83918
S142
D
S
P
Q
E
C
L
S
P
F
G
R
P
T
M
Zebra Danio
Brachydanio rerio
NP_571480
739
83196
S142
G
S
P
Q
E
C
L
S
P
F
S
R
P
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392355
1146
126812
Q186
S
A
L
A
L
Q
E
Q
P
N
N
N
N
S
I
Nematode Worm
Caenorhab. elegans
P34522
586
65798
S78
G
A
S
T
S
V
S
S
N
S
S
S
S
S
S
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
S145
E
E
C
N
G
S
T
S
P
I
Q
E
T
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
33.2
99.3
N.A.
98.3
77.6
N.A.
95.6
93.6
87.9
82.6
N.A.
N.A.
23.4
26.5
35
Protein Similarity:
100
46
46.5
99.5
N.A.
99.4
78.5
N.A.
98
96.1
93.7
89.3
N.A.
N.A.
36.9
45
51
P-Site Identity:
100
13.3
13.3
100
N.A.
100
6.6
N.A.
100
93.3
93.3
73.3
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
100
33.3
26.6
100
N.A.
100
20
N.A.
100
93.3
93.3
80
N.A.
N.A.
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
0
0
0
0
0
8
16
0
16
0
0
% A
% Cys:
0
0
8
0
0
54
0
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% D
% Glu:
8
8
0
0
54
0
8
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
0
0
0
16
0
47
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% I
% Lys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
16
0
16
0
8
24
62
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% M
% Asn:
8
0
0
24
0
0
0
0
8
16
16
8
8
0
0
% N
% Pro:
0
0
70
31
16
0
0
16
70
0
0
0
54
0
0
% P
% Gln:
0
0
0
24
0
8
0
8
0
0
8
16
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
8
0
0
54
0
0
0
% R
% Ser:
8
70
8
0
8
8
8
70
0
16
16
16
8
24
8
% S
% Thr:
0
0
0
8
0
0
8
0
0
0
0
0
8
47
8
% T
% Val:
0
8
0
0
0
8
16
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _