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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX1
All Species:
15.76
Human Site:
S453
Identified Species:
28.89
UniProt:
Q92786
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92786
NP_002754.2
737
83203
S453
N
S
S
D
Q
S
A
S
G
P
A
A
G
G
H
Chimpanzee
Pan troglodytes
XP_522907
592
65532
P317
D
S
P
R
Y
L
I
P
P
R
M
I
P
K
P
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
P317
D
S
P
R
Y
P
I
P
P
R
M
I
P
K
R
Dog
Lupus familis
XP_858135
737
83203
S453
N
S
S
D
Q
S
A
S
G
P
P
A
G
G
H
Cat
Felis silvestris
Mouse
Mus musculus
P48437
737
83108
S453
N
S
S
E
Q
S
A
S
G
P
A
T
G
G
H
Rat
Rattus norvegicus
NP_001100671
583
64827
I308
E
L
D
P
G
Q
F
I
D
R
A
R
A
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511202
735
83058
A451
K
N
S
S
D
Q
S
A
S
G
P
P
A
G
H
Chicken
Gallus gallus
Q91018
736
83123
S452
N
S
S
D
Q
P
A
S
A
P
P
A
G
G
H
Frog
Xenopus laevis
NP_001084172
740
83918
S454
N
S
N
D
Q
S
A
S
G
P
P
P
G
S
H
Zebra Danio
Brachydanio rerio
NP_571480
739
83196
L455
S
S
D
Q
T
G
S
L
S
T
P
G
G
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392355
1146
126812
P864
G
S
E
S
P
P
P
P
P
P
P
R
S
Y
H
Nematode Worm
Caenorhab. elegans
P34522
586
65798
N311
F
H
P
I
F
P
A
N
P
L
F
H
M
A
P
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
G440
A
S
G
G
F
H
P
G
D
F
P
M
K
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
33.2
99.3
N.A.
98.3
77.6
N.A.
95.6
93.6
87.9
82.6
N.A.
N.A.
23.4
26.5
35
Protein Similarity:
100
46
46.5
99.5
N.A.
99.4
78.5
N.A.
98
96.1
93.7
89.3
N.A.
N.A.
36.9
45
51
P-Site Identity:
100
6.6
6.6
93.3
N.A.
86.6
6.6
N.A.
20
80
73.3
20
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
93.3
6.6
N.A.
40
80
80
33.3
N.A.
N.A.
20
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
47
8
8
0
24
24
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
16
31
8
0
0
0
16
0
0
0
0
0
0
% D
% Glu:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
8
0
0
0
16
0
8
0
0
8
8
0
0
0
0
% F
% Gly:
8
0
8
8
8
8
0
8
31
8
0
8
47
39
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
8
0
8
62
% H
% Ile:
0
0
0
8
0
0
16
8
0
0
0
16
0
0
8
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
8
16
0
% K
% Leu:
0
8
0
0
0
8
0
8
0
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
8
8
0
0
% M
% Asn:
39
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
24
8
8
31
16
24
31
47
54
16
16
8
16
% P
% Gln:
0
0
0
8
39
16
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
16
0
0
0
0
0
24
0
16
0
0
8
% R
% Ser:
8
77
39
16
0
31
16
39
16
0
0
0
8
8
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _