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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX1
All Species:
13.03
Human Site:
S505
Identified Species:
23.89
UniProt:
Q92786
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92786
NP_002754.2
737
83203
S505
G
A
P
S
G
S
F
S
G
K
D
R
A
S
P
Chimpanzee
Pan troglodytes
XP_522907
592
65532
S369
S
P
P
Q
D
S
S
S
Q
R
H
P
S
S
E
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
S369
S
P
P
Q
D
S
S
S
Q
R
H
P
S
S
E
Dog
Lupus familis
XP_858135
737
83203
S505
G
A
P
S
G
S
F
S
G
K
D
R
A
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P48437
737
83108
S505
G
A
P
S
G
S
F
S
G
K
D
R
A
S
P
Rat
Rattus norvegicus
NP_001100671
583
64827
M360
K
Q
E
L
N
T
A
M
S
Q
V
V
D
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511202
735
83058
P503
G
A
P
S
G
S
F
P
G
K
D
R
A
S
P
Chicken
Gallus gallus
Q91018
736
83123
P504
G
A
P
S
A
S
F
P
G
K
E
R
A
S
P
Frog
Xenopus laevis
NP_001084172
740
83918
Q506
G
A
P
F
I
S
F
Q
G
K
D
S
S
S
P
Zebra Danio
Brachydanio rerio
NP_571480
739
83196
Y507
L
G
A
P
T
G
P
Y
P
G
K
D
R
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392355
1146
126812
P916
A
G
H
P
G
Q
V
P
P
P
G
P
H
H
L
Nematode Worm
Caenorhab. elegans
P34522
586
65798
E363
K
K
K
R
T
K
V
E
I
K
K
E
D
A
M
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
G492
F
E
S
L
R
Y
P
G
S
P
L
I
A
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
33.2
99.3
N.A.
98.3
77.6
N.A.
95.6
93.6
87.9
82.6
N.A.
N.A.
23.4
26.5
35
Protein Similarity:
100
46
46.5
99.5
N.A.
99.4
78.5
N.A.
98
96.1
93.7
89.3
N.A.
N.A.
36.9
45
51
P-Site Identity:
100
26.6
26.6
100
N.A.
100
0
N.A.
93.3
80
66.6
6.6
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
100
40
40
100
N.A.
100
20
N.A.
93.3
86.6
73.3
6.6
N.A.
N.A.
6.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
47
8
0
8
0
8
0
0
0
0
0
47
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
0
0
0
0
39
8
16
0
0
% D
% Glu:
0
8
8
0
0
0
0
8
0
0
8
8
0
0
16
% E
% Phe:
8
0
0
8
0
0
47
0
0
0
0
0
0
0
0
% F
% Gly:
47
16
0
0
39
8
0
8
47
8
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
16
0
8
8
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
16
8
8
0
0
8
0
0
0
54
16
0
0
0
0
% K
% Leu:
8
0
0
16
0
0
0
0
0
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
16
62
16
0
0
16
24
16
16
0
24
0
0
47
% P
% Gln:
0
8
0
16
0
8
0
8
16
8
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
16
0
39
8
0
0
% R
% Ser:
16
0
8
39
0
62
16
39
16
0
0
8
24
70
16
% S
% Thr:
0
0
0
0
16
8
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
16
0
0
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _