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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROX1 All Species: 26.06
Human Site: S511 Identified Species: 47.78
UniProt: Q92786 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92786 NP_002754.2 737 83203 S511 F S G K D R A S P E S L D L T
Chimpanzee Pan troglodytes XP_522907 592 65532 S375 S S Q R H P S S E P A L R P W
Rhesus Macaque Macaca mulatta XP_001088672 592 65588 S375 S S Q R H P S S E P A R R P W
Dog Lupus familis XP_858135 737 83203 S511 F S G K D R A S P E S L D L T
Cat Felis silvestris
Mouse Mus musculus P48437 737 83108 S511 F S G K D R A S P E S L D L T
Rat Rattus norvegicus NP_001100671 583 64827 T366 A M S Q V V D T V V K V F S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511202 735 83058 S509 F P G K D R A S P E S L D L T
Chicken Gallus gallus Q91018 736 83123 S510 F P G K E R A S P E S L D L T
Frog Xenopus laevis NP_001084172 740 83918 S512 F Q G K D S S S P E S L D L T
Zebra Danio Brachydanio rerio NP_571480 739 83196 S513 P Y P G K D R S S P E S L D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392355 1146 126812 H922 V P P P G P H H L P A S P P G
Nematode Worm Caenorhab. elegans P34522 586 65798 A369 V E I K K E D A M S S R A S P
Sea Urchin Strong. purpuratus XP_781578 723 81042 N498 P G S P L I A N S H L S P L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.6 33.2 99.3 N.A. 98.3 77.6 N.A. 95.6 93.6 87.9 82.6 N.A. N.A. 23.4 26.5 35
Protein Similarity: 100 46 46.5 99.5 N.A. 99.4 78.5 N.A. 98 96.1 93.7 89.3 N.A. N.A. 36.9 45 51
P-Site Identity: 100 20 13.3 100 N.A. 100 0 N.A. 93.3 86.6 80 6.6 N.A. N.A. 0 13.3 13.3
P-Site Similarity: 100 40 33.3 100 N.A. 100 20 N.A. 93.3 93.3 86.6 6.6 N.A. N.A. 6.6 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 47 8 0 0 24 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 39 8 16 0 0 0 0 0 47 8 0 % D
% Glu: 0 8 0 0 8 8 0 0 16 47 8 0 0 0 0 % E
% Phe: 47 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 8 47 8 8 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 16 0 8 8 0 8 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 54 16 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 0 8 0 8 54 8 54 8 % L
% Met: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 16 24 16 16 0 24 0 0 47 31 0 0 16 24 8 % P
% Gln: 0 8 16 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 16 0 39 8 0 0 0 0 16 16 0 0 % R
% Ser: 16 39 16 0 0 8 24 70 16 8 54 24 0 16 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 47 % T
% Val: 16 0 0 0 8 8 0 0 8 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _