KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX1
All Species:
21.52
Human Site:
S649
Identified Species:
39.44
UniProt:
Q92786
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92786
NP_002754.2
737
83203
S649
A
I
N
D
G
V
T
S
T
E
E
L
S
I
T
Chimpanzee
Pan troglodytes
XP_522907
592
65532
L513
G
V
T
N
P
K
M
L
V
V
L
R
N
S
E
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
L513
G
V
T
N
P
K
M
L
V
V
L
R
N
S
E
Dog
Lupus familis
XP_858135
737
83203
S649
A
I
N
D
G
V
T
S
T
E
E
L
S
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P48437
737
83108
S649
A
I
N
D
G
V
T
S
T
E
E
L
S
I
T
Rat
Rattus norvegicus
NP_001100671
583
64827
F504
L
G
A
P
S
G
S
F
S
G
K
D
R
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511202
735
83058
S647
A
I
N
D
G
V
T
S
T
E
E
L
S
I
T
Chicken
Gallus gallus
Q91018
736
83123
S648
A
I
N
D
G
V
T
S
T
E
E
L
S
I
T
Frog
Xenopus laevis
NP_001084172
740
83918
I650
R
Q
A
I
N
D
G
I
T
S
T
E
E
L
C
Zebra Danio
Brachydanio rerio
NP_571480
739
83196
G651
A
I
N
D
G
V
T
G
S
E
E
L
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392355
1146
126812
N1060
A
V
S
E
G
V
K
N
A
D
D
L
R
V
G
Nematode Worm
Caenorhab. elegans
P34522
586
65798
K507
R
N
D
I
F
V
S
K
D
S
E
L
F
K
V
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
T636
S
V
S
D
N
V
E
T
A
E
D
L
K
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
33.2
99.3
N.A.
98.3
77.6
N.A.
95.6
93.6
87.9
82.6
N.A.
N.A.
23.4
26.5
35
Protein Similarity:
100
46
46.5
99.5
N.A.
99.4
78.5
N.A.
98
96.1
93.7
89.3
N.A.
N.A.
36.9
45
51
P-Site Identity:
100
0
0
100
N.A.
100
0
N.A.
100
100
6.6
73.3
N.A.
N.A.
26.6
20
33.3
P-Site Similarity:
100
20
20
100
N.A.
100
26.6
N.A.
100
100
13.3
93.3
N.A.
N.A.
73.3
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
16
0
0
0
0
0
16
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
8
54
0
8
0
0
8
8
16
8
0
0
0
% D
% Glu:
0
0
0
8
0
0
8
0
0
54
54
8
8
0
16
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
16
8
0
0
54
8
8
8
0
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
47
0
16
0
0
0
8
0
0
0
0
0
39
0
% I
% Lys:
0
0
0
0
0
16
8
8
0
0
8
0
8
8
0
% K
% Leu:
8
0
0
0
0
0
0
16
0
0
16
70
0
8
0
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
47
16
16
0
0
8
0
0
0
0
16
0
0
% N
% Pro:
0
0
0
8
16
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
0
0
0
0
0
0
0
0
16
16
0
0
% R
% Ser:
8
0
16
0
8
0
16
39
16
16
0
0
47
16
16
% S
% Thr:
0
0
16
0
0
0
47
8
47
0
8
0
0
0
47
% T
% Val:
0
31
0
0
0
70
0
0
16
16
0
0
0
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _