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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX1
All Species:
32.73
Human Site:
Y597
Identified Species:
60
UniProt:
Q92786
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92786
NP_002754.2
737
83203
Y597
L
M
F
F
Y
T
R
Y
P
S
S
N
M
L
K
Chimpanzee
Pan troglodytes
XP_522907
592
65532
N461
F
T
R
Y
P
S
S
N
L
L
K
V
Y
F
P
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
N461
F
A
R
Y
P
S
S
N
L
L
K
A
Y
F
P
Dog
Lupus familis
XP_858135
737
83203
Y597
L
M
F
F
Y
T
R
Y
P
S
S
N
M
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P48437
737
83108
Y597
L
M
F
F
Y
T
R
Y
P
S
S
N
M
L
K
Rat
Rattus norvegicus
NP_001100671
583
64827
A452
K
N
S
S
E
Q
S
A
S
G
P
A
T
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511202
735
83058
Y595
L
M
F
F
Y
T
R
Y
P
S
S
N
M
L
K
Chicken
Gallus gallus
Q91018
736
83123
Y596
L
M
F
F
Y
T
R
Y
P
S
S
N
M
L
K
Frog
Xenopus laevis
NP_001084172
740
83918
T598
A
K
L
M
F
F
Y
T
R
Y
P
S
S
N
M
Zebra Danio
Brachydanio rerio
NP_571480
739
83196
Y599
L
M
F
F
Y
T
R
Y
P
S
S
N
M
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392355
1146
126812
Y1008
L
M
F
F
W
V
R
Y
P
S
S
S
I
L
K
Nematode Worm
Caenorhab. elegans
P34522
586
65798
S455
P
N
S
N
L
L
K
S
Y
F
P
D
I
R
F
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
Y584
L
M
F
F
F
T
R
Y
P
S
S
A
L
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
33.2
99.3
N.A.
98.3
77.6
N.A.
95.6
93.6
87.9
82.6
N.A.
N.A.
23.4
26.5
35
Protein Similarity:
100
46
46.5
99.5
N.A.
99.4
78.5
N.A.
98
96.1
93.7
89.3
N.A.
N.A.
36.9
45
51
P-Site Identity:
100
0
0
100
N.A.
100
0
N.A.
100
100
0
100
N.A.
N.A.
73.3
0
73.3
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
0
N.A.
100
100
13.3
100
N.A.
N.A.
93.3
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
0
0
0
24
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
16
0
62
62
16
8
0
0
0
8
0
0
0
16
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% I
% Lys:
8
8
0
0
0
0
8
0
0
0
16
0
0
0
54
% K
% Leu:
62
0
8
0
8
8
0
0
16
16
0
0
8
62
0
% L
% Met:
0
62
0
8
0
0
0
0
0
0
0
0
47
0
8
% M
% Asn:
0
16
0
8
0
0
0
16
0
0
0
47
0
8
0
% N
% Pro:
8
0
0
0
16
0
0
0
62
0
24
0
0
0
16
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
16
0
0
0
62
0
8
0
0
0
0
8
8
% R
% Ser:
0
0
16
8
0
16
24
8
8
62
62
16
8
0
0
% S
% Thr:
0
8
0
0
0
54
0
8
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
47
0
8
62
8
8
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _