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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROX1
All Species:
25.76
Human Site:
Y662
Identified Species:
47.22
UniProt:
Q92786
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92786
NP_002754.2
737
83203
Y662
I
T
R
D
C
E
L
Y
R
A
L
N
M
H
Y
Chimpanzee
Pan troglodytes
XP_522907
592
65532
N526
S
E
L
F
R
A
L
N
M
H
Y
N
K
G
N
Rhesus Macaque
Macaca mulatta
XP_001088672
592
65588
N526
S
E
L
F
R
A
L
N
M
H
Y
N
K
G
N
Dog
Lupus familis
XP_858135
737
83203
Y662
I
T
R
D
C
E
L
Y
R
A
L
N
M
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
P48437
737
83108
Y662
I
T
R
D
C
E
L
Y
R
A
L
N
M
H
Y
Rat
Rattus norvegicus
NP_001100671
583
64827
L517
A
S
P
E
S
L
D
L
T
R
D
T
T
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511202
735
83058
Y660
I
T
R
D
C
E
L
Y
R
A
L
N
M
H
Y
Chicken
Gallus gallus
Q91018
736
83123
Y661
I
T
R
D
C
E
L
Y
R
A
L
N
M
H
Y
Frog
Xenopus laevis
NP_001084172
740
83918
E663
L
C
I
T
R
D
C
E
L
Y
R
A
L
N
M
Zebra Danio
Brachydanio rerio
NP_571480
739
83196
F664
V
S
R
D
C
E
L
F
R
A
L
N
M
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392355
1146
126812
Y1073
V
G
G
D
S
E
I
Y
R
V
L
N
L
H
Y
Nematode Worm
Caenorhab. elegans
P34522
586
65798
N520
K
V
L
N
T
H
Y
N
R
N
N
H
I
K
A
Sea Urchin
Strong. purpuratus
XP_781578
723
81042
Y649
V
T
R
D
S
E
L
Y
R
S
L
N
L
H
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
33.2
99.3
N.A.
98.3
77.6
N.A.
95.6
93.6
87.9
82.6
N.A.
N.A.
23.4
26.5
35
Protein Similarity:
100
46
46.5
99.5
N.A.
99.4
78.5
N.A.
98
96.1
93.7
89.3
N.A.
N.A.
36.9
45
51
P-Site Identity:
100
13.3
13.3
100
N.A.
100
0
N.A.
100
100
0
80
N.A.
N.A.
53.3
6.6
73.3
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
13.3
N.A.
100
100
26.6
100
N.A.
N.A.
73.3
26.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
16
0
0
0
47
0
8
0
0
8
% A
% Cys:
0
8
0
0
47
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
0
8
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
16
0
8
0
62
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
16
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
0
0
0
0
0
0
16
0
% G
% His:
0
0
0
0
0
8
0
0
0
16
0
8
0
62
0
% H
% Ile:
39
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
16
8
0
% K
% Leu:
8
0
24
0
0
8
70
8
8
0
62
0
24
0
8
% L
% Met:
0
0
0
0
0
0
0
0
16
0
0
0
47
0
8
% M
% Asn:
0
0
0
8
0
0
0
24
0
8
8
77
0
8
16
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
54
0
24
0
0
0
70
8
8
0
0
0
0
% R
% Ser:
16
16
0
0
24
0
0
0
0
8
0
0
0
8
0
% S
% Thr:
0
47
0
8
8
0
0
0
8
0
0
8
8
0
0
% T
% Val:
24
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
54
0
8
16
0
0
0
62
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _