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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SC65 All Species: 23.64
Human Site: Y296 Identified Species: 57.78
UniProt: Q92791 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92791 NP_006446.1 437 50381 Y296 D K F V A T M Y H Y L Q F A Y
Chimpanzee Pan troglodytes XP_001144364 368 42372 M251 A R S A A S Y M L F D P K D S
Rhesus Macaque Macaca mulatta XP_001093403 419 48074 Y296 D K F V A T M Y H Y L Q F A Y
Dog Lupus familis XP_849608 443 50452 Y302 E K F V A T M Y H Y L Q F A Y
Cat Felis silvestris
Mouse Mus musculus Q8K2B0 443 51113 Y302 D K F V A T M Y H Y L Q F A Y
Rat Rattus norvegicus Q64375 414 47756 Y273 D K F V A T M Y H Y L Q F A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520238 316 35640 T199 V D C E A D L T P N V G G Y F
Chicken Gallus gallus Q90830 271 31475 A154 K A N N L P K A I A A A H T F
Frog Xenopus laevis NP_001087150 428 50083 Y294 Q K F V A T M Y H Y L Q F A Y
Zebra Danio Brachydanio rerio NP_001119910 426 50165 F293 D K F V A T M F H Y M Q F A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.3 87.4 90.5 N.A. 91.1 84.9 N.A. 50.7 33.1 57.4 53 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 83.7 90.1 93.6 N.A. 94.1 88.3 N.A. 56.7 44.8 72 68.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 100 100 N.A. 6.6 0 93.3 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 26.6 6.6 93.3 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 90 0 0 10 0 10 10 10 0 70 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 10 0 0 0 10 0 0 0 0 10 0 0 10 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 70 0 0 0 0 10 0 10 0 0 70 0 20 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 70 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 10 70 0 0 0 0 10 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 0 10 0 10 0 10 0 60 0 0 0 0 % L
% Met: 0 0 0 0 0 0 70 10 0 0 10 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 10 0 0 10 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 70 0 10 0 0 0 0 0 10 0 % T
% Val: 10 0 0 70 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 60 0 70 0 0 0 10 70 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _