KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
18.18
Human Site:
S2138
Identified Species:
33.33
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
S2138
P
G
M
H
Q
Q
P
S
L
Q
N
L
N
A
M
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
S2138
P
G
M
H
Q
Q
P
S
L
Q
N
L
N
A
M
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
S2138
P
G
M
H
Q
Q
P
S
L
Q
N
L
N
A
M
Dog
Lupus familis
XP_851777
2404
260682
G2104
P
S
L
H
Q
Q
P
G
L
Q
N
L
N
A
I
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S2139
P
G
M
H
Q
Q
P
S
L
Q
N
L
N
A
M
Rat
Rattus norvegicus
NP_596872
2444
265618
S2139
P
G
M
H
Q
Q
P
S
L
Q
N
L
N
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
G2146
Q
T
G
M
Q
Q
P
G
M
H
A
Q
P
G
L
Frog
Xenopus laevis
NP_001088637
2428
264402
N2141
H
P
Q
A
G
L
Q
N
M
S
P
M
P
V
G
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
R1880
M
Y
R
R
Q
L
L
R
H
Q
Q
Q
Q
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
G2803
P
G
A
G
G
G
G
G
S
A
T
G
G
G
L
Honey Bee
Apis mellifera
XP_001122031
2606
284119
M2342
Q
P
G
L
Q
H
M
M
S
Q
Q
Q
Q
Q
Q
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
Q1825
V
H
G
M
G
Q
N
Q
P
V
R
N
N
Q
D
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
M2354
Q
P
V
P
Q
Q
Q
M
A
Q
P
N
M
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
73.3
N.A.
100
100
N.A.
N.A.
20
0
13.3
N.A.
13.3
13.3
13.3
20
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
33.3
20
13.3
N.A.
20
13.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
8
8
8
0
0
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
47
24
8
24
8
8
24
0
0
0
8
8
16
8
% G
% His:
8
8
0
47
0
8
0
0
8
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
0
16
8
0
47
0
0
47
0
0
16
% L
% Met:
8
0
39
16
0
0
8
16
16
0
0
8
8
0
39
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
47
16
54
0
0
% N
% Pro:
54
24
0
8
0
0
54
0
8
0
16
0
16
0
0
% P
% Gln:
24
0
8
0
77
70
16
8
0
70
16
24
16
31
24
% Q
% Arg:
0
0
8
8
0
0
0
8
0
0
8
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
39
16
8
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
8
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _