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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
33.64
Human Site:
S2421
Identified Species:
61.67
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
S2421
T
P
S
R
S
A
L
S
S
E
L
S
L
V
G
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
S2421
T
P
S
R
S
A
L
S
S
E
L
S
L
V
G
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
S2421
T
P
S
R
S
A
L
S
S
E
L
S
L
V
G
Dog
Lupus familis
XP_851777
2404
260682
S2383
T
P
N
R
S
A
L
S
S
E
L
S
L
V
G
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S2420
T
P
N
R
S
A
L
S
S
E
L
S
L
V
G
Rat
Rattus norvegicus
NP_596872
2444
265618
S2423
T
P
N
R
S
A
L
S
S
E
L
S
L
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
S2426
T
P
N
R
S
A
L
S
N
E
L
S
L
V
G
Frog
Xenopus laevis
NP_001088637
2428
264402
T2407
P
P
N
R
S
A
L
T
N
D
L
S
L
V
G
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
S2091
P
N
R
G
G
L
P
S
D
L
N
M
V
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
G3245
V
G
V
G
V
G
V
G
V
N
V
N
V
G
N
Honey Bee
Apis mellifera
XP_001122031
2606
284119
T2585
A
P
P
P
T
S
G
T
D
S
S
E
V
T
P
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
L2036
R
I
D
C
P
R
F
L
Y
F
P
F
F
L
N
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
K2597
T
P
M
G
H
S
N
K
N
S
L
Q
S
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
66.6
6.6
N.A.
0
6.6
0
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
13.3
N.A.
26.6
33.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
62
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
16
8
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
54
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
0
8
8
0
0
% F
% Gly:
0
8
0
24
8
8
8
8
0
0
0
0
0
16
62
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
62
8
0
8
70
0
62
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
39
0
0
0
8
0
24
8
8
8
0
0
16
% N
% Pro:
16
77
8
8
8
0
8
0
0
0
8
0
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
8
62
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
24
0
62
16
0
62
47
16
8
62
8
0
0
% S
% Thr:
62
0
0
0
8
0
0
16
0
0
0
0
0
8
0
% T
% Val:
8
0
8
0
8
0
8
0
8
0
8
0
24
62
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _