KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYMPK
All Species:
7.88
Human Site:
S1243
Identified Species:
21.67
UniProt:
Q92797
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92797
NP_004810.2
1274
141148
S1243
L
T
L
K
E
E
R
S
P
Q
T
L
A
P
V
Chimpanzee
Pan troglodytes
XP_001166963
1274
141112
S1243
L
T
L
K
E
E
R
S
P
Q
T
L
A
P
I
Rhesus Macaque
Macaca mulatta
XP_001118586
911
100387
P881
T
S
K
E
E
R
S
P
Q
T
L
A
P
I
G
Dog
Lupus familis
XP_533638
1275
141152
P1245
T
S
K
E
E
R
S
P
Q
T
L
A
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80X82
1284
142265
D1253
A
V
G
S
S
S
K
D
E
R
S
P
Q
N
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYV9
1202
134433
P1172
K
S
Q
G
K
E
E
P
Q
E
D
S
S
S
N
Zebra Danio
Brachydanio rerio
XP_699475
1247
139680
S1205
V
S
E
E
A
P
Q
S
S
P
V
A
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625131
567
63847
F537
P
C
D
M
H
D
E
F
D
I
A
P
P
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783721
1245
140093
S1179
E
D
M
E
E
K
T
S
E
E
M
E
T
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
70.7
97.2
N.A.
94
N.A.
N.A.
N.A.
N.A.
68.4
66.4
N.A.
N.A.
28.8
N.A.
46.5
Protein Similarity:
100
100
70.9
97.9
N.A.
96.2
N.A.
N.A.
N.A.
N.A.
81.3
78.7
N.A.
N.A.
35.8
N.A.
64
P-Site Identity:
100
93.3
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
20
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
33.3
N.A.
N.A.
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
0
0
12
34
23
12
12
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
0
0
12
0
12
12
0
12
0
0
0
12
% D
% Glu:
12
0
12
45
56
34
23
0
23
23
0
12
12
12
12
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
12
0
0
0
0
0
0
0
0
0
12
23
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
12
% I
% Lys:
12
0
23
23
12
12
12
0
0
0
0
0
0
12
0
% K
% Leu:
23
0
23
0
0
0
0
0
0
0
23
23
0
0
12
% L
% Met:
0
0
12
12
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% N
% Pro:
12
0
0
0
0
12
0
34
23
12
0
23
34
23
0
% P
% Gln:
0
0
12
0
0
0
12
0
34
23
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
23
23
0
0
12
0
0
0
0
0
% R
% Ser:
0
45
0
12
12
12
23
45
12
0
12
12
12
12
0
% S
% Thr:
23
23
0
0
0
0
12
0
0
23
23
0
12
0
0
% T
% Val:
12
12
0
0
0
0
0
0
0
0
12
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _