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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYMPK
All Species:
20.91
Human Site:
T554
Identified Species:
57.5
UniProt:
Q92797
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92797
NP_004810.2
1274
141148
T554
S
D
V
L
K
P
L
T
D
A
Q
V
E
A
M
Chimpanzee
Pan troglodytes
XP_001166963
1274
141112
T554
S
D
V
L
K
P
L
T
D
A
Q
V
E
A
M
Rhesus Macaque
Macaca mulatta
XP_001118586
911
100387
K297
L
Q
E
K
P
D
Q
K
D
G
I
F
T
K
V
Dog
Lupus familis
XP_533638
1275
141152
T554
S
D
V
L
K
P
L
T
D
A
Q
V
E
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q80X82
1284
142265
T554
S
D
V
L
K
P
L
T
D
A
Q
V
E
A
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYV9
1202
134433
T548
K
E
V
T
E
P
L
T
D
V
Q
I
K
S
L
Zebra Danio
Brachydanio rerio
XP_699475
1247
139680
S552
A
D
V
V
Q
P
F
S
E
V
Q
I
E
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625131
567
63847
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783721
1245
140093
H515
D
D
A
N
K
L
A
H
G
A
V
K
R
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
70.7
97.2
N.A.
94
N.A.
N.A.
N.A.
N.A.
68.4
66.4
N.A.
N.A.
28.8
N.A.
46.5
Protein Similarity:
100
100
70.9
97.9
N.A.
96.2
N.A.
N.A.
N.A.
N.A.
81.3
78.7
N.A.
N.A.
35.8
N.A.
64
P-Site Identity:
100
100
6.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
40
33.3
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
100
13.3
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
80
80
N.A.
N.A.
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
12
0
0
56
0
0
0
45
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
67
0
0
0
12
0
0
67
0
0
0
0
0
0
% D
% Glu:
0
12
12
0
12
0
0
0
12
0
0
0
56
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
23
0
12
12
% I
% Lys:
12
0
0
12
56
0
0
12
0
0
0
12
12
23
0
% K
% Leu:
12
0
0
45
0
12
56
0
0
0
0
0
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
67
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
12
0
12
0
0
0
67
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
45
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% S
% Thr:
0
0
0
12
0
0
0
56
0
0
0
0
12
0
0
% T
% Val:
0
0
67
12
0
0
0
0
0
23
12
45
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _