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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GGH All Species: 29.7
Human Site: S105 Identified Species: 59.39
UniProt: Q92820 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92820 NP_003869.1 318 35964 S105 G S V D L R R S D Y A K V A K
Chimpanzee Pan troglodytes XP_519786 318 35999 S105 G S V D L R R S D Y A K V A K
Rhesus Macaque Macaca mulatta XP_001091897 318 36112 S105 G S V D L R R S D Y A K V A K
Dog Lupus familis XP_535087 318 35655 S105 G S V D L K K S G Y A L A A K
Cat Felis silvestris
Mouse Mus musculus Q9Z0L8 317 35419 S104 G G A N L T D S G Y S R V A K
Rat Rattus norvegicus Q62867 317 35812 S104 G G A N L T H S G Y S R V A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513787 279 31697 R70 L Q T S Q Y A R V A K L L Y N
Chicken Gallus gallus XP_419226 439 48191 S226 G G V D L K T S E Y S R V A K
Frog Xenopus laevis NP_001086160 315 35774 S103 G A V D L V K S E Y A R V A K
Zebra Danio Brachydanio rerio NP_998487 312 35365 S100 G G V S L E S S G Y S K A A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787753 289 32270 H80 V G Y S G A A H I L Y H L A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65355 347 38624 Y128 G W A K E G L Y F E I V K K I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.5 76 N.A. 68.8 67.9 N.A. 55.9 42.3 58.8 54 N.A. N.A. N.A. N.A. 41.8
Protein Similarity: 100 99.6 98.4 83.3 N.A. 84.5 81.1 N.A. 70.4 56.4 75.7 69.1 N.A. N.A. N.A. N.A. 56.9
P-Site Identity: 100 100 100 66.6 N.A. 46.6 46.6 N.A. 0 60 66.6 46.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 80 N.A. 66.6 66.6 N.A. 6.6 86.6 93.3 53.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 25 0 0 9 17 0 0 9 42 0 17 84 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 0 0 9 0 25 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 9 0 0 17 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 84 42 0 0 9 9 0 0 34 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 9 9 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 9 % I
% Lys: 0 0 0 9 0 17 17 0 0 0 9 34 9 9 67 % K
% Leu: 9 0 0 0 75 0 9 0 0 9 0 17 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 25 25 9 0 0 0 34 0 0 0 % R
% Ser: 0 34 0 25 0 0 9 75 0 0 34 0 0 0 0 % S
% Thr: 0 0 9 0 0 17 9 0 0 0 0 0 0 0 0 % T
% Val: 9 0 59 0 0 9 0 0 9 0 0 9 59 0 9 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 9 0 9 0 75 9 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _