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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCSK5
All Species:
21.52
Human Site:
T624
Identified Species:
39.44
UniProt:
Q92824
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92824
NP_006191.2
913
101649
T624
Y
S
R
V
E
D
P
T
D
D
Y
G
T
E
D
Chimpanzee
Pan troglodytes
XP_520079
1860
206955
T624
Y
S
R
V
E
D
P
T
D
D
Y
G
T
E
D
Rhesus Macaque
Macaca mulatta
XP_001094068
794
86687
A525
A
R
P
H
D
Y
S
A
D
G
F
N
D
W
A
Dog
Lupus familis
XP_541276
1883
209497
T622
Y
S
R
V
E
D
P
T
D
D
Y
G
T
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q04592
1877
209270
T626
Y
S
R
V
E
D
P
T
D
D
Y
G
A
E
D
Rat
Rattus norvegicus
P41413
1877
199778
T626
Y
S
R
V
E
D
P
T
D
D
Y
G
A
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507677
642
72067
W373
A
H
L
K
T
N
D
W
K
I
N
G
A
G
R
Chicken
Gallus gallus
XP_424841
1853
207276
T616
S
S
P
V
E
D
P
T
E
D
Y
G
T
D
D
Frog
Xenopus laevis
P29119
783
86425
L514
M
G
T
R
S
C
L
L
A
P
R
P
H
D
Y
Zebra Danio
Brachydanio rerio
NP_001077298
917
101996
E629
Q
P
D
D
E
Y
S
E
E
Y
V
G
T
C
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30432
1679
183351
P875
R
S
P
S
S
S
N
P
F
L
F
P
S
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
V658
V
H
Q
L
T
S
Q
V
E
E
S
A
R
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
V544
G
V
V
R
P
R
D
V
S
S
E
G
F
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.8
42.8
44
N.A.
45.8
45.4
N.A.
46.9
39.4
42.2
70.6
N.A.
29
N.A.
35.7
N.A.
Protein Similarity:
100
49
54.4
45.1
N.A.
47.4
46.7
N.A.
57
43.5
55.5
81.9
N.A.
37.1
N.A.
48
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
93.3
93.3
N.A.
6.6
73.3
0
20
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
20
100
N.A.
93.3
93.3
N.A.
13.3
86.6
6.6
26.6
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
8
8
0
0
8
24
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
8
8
47
16
0
47
47
0
0
8
16
54
% D
% Glu:
0
0
0
0
54
0
0
8
24
8
8
0
0
39
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
16
0
8
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
0
8
0
70
0
8
0
% G
% His:
0
16
0
8
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% K
% Leu:
0
0
8
8
0
0
8
8
0
8
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
8
8
0
0
0
% N
% Pro:
0
8
24
0
8
0
47
8
0
8
0
16
0
0
0
% P
% Gln:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
39
16
0
8
0
0
0
0
8
0
8
0
8
% R
% Ser:
8
54
0
8
16
16
16
0
8
8
8
0
8
8
16
% S
% Thr:
0
0
8
0
16
0
0
47
0
0
0
0
39
0
0
% T
% Val:
8
8
8
47
0
0
0
16
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
39
0
0
0
0
16
0
0
0
8
47
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _