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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT2A All Species: 31.82
Human Site: S528 Identified Species: 58.33
UniProt: Q92830 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92830 NP_066564.2 837 93926 S528 V G L Q N V F S H Q L P R M P
Chimpanzee Pan troglodytes XP_511500 837 93951 S528 V G L Q N V F S H Q L P R M P
Rhesus Macaque Macaca mulatta XP_001086807 858 97361 S549 V G L Q N V F S H Q L P R M P
Dog Lupus familis XP_548094 837 93980 S528 V G L Q N V F S H Q L P R M P
Cat Felis silvestris
Mouse Mus musculus Q9JHD2 830 93373 S521 V G L Q N V F S H Q L P R M P
Rat Rattus norvegicus NP_001100520 832 93633 S523 V G L Q N V F S H Q L P R M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515022 677 76679 K395 H K T L A L I K D G R V I G G
Chicken Gallus gallus NP_989660 804 91104 S495 V G L Q N V F S H Q L P R M P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922732 795 90605 R491 V F S H Q L P R M P K E Y I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648586 813 92151 A499 L G L Q L V F A Y Q L P E M P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784879 808 92092 S499 V G L Q N V F S H Q L P R M P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9AR19 568 63105 K286 Y R P Y H S Q K F G E I A F C
Baker's Yeast Sacchar. cerevisiae Q03330 439 51051 V157 V I R K P L T V V G G I T Y R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 67.3 98.4 N.A. 97 97.9 N.A. 71.8 85.4 N.A. 81.1 N.A. 45.8 N.A. N.A. 59.1
Protein Similarity: 100 99.5 77.2 98.9 N.A. 97.7 98.3 N.A. 75.3 90.5 N.A. 86 N.A. 64.6 N.A. N.A. 74.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 100 N.A. 6.6 N.A. 66.6 N.A. N.A. 100
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 N.A. 20 N.A. 86.6 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 28.6 26 N.A.
Protein Similarity: N.A. N.A. N.A. 45.5 36.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 8 8 0 0 % E
% Phe: 0 8 0 0 0 0 70 0 8 0 0 0 0 8 0 % F
% Gly: 0 70 0 0 0 0 0 0 0 24 8 0 0 8 8 % G
% His: 8 0 0 8 8 0 0 0 62 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 0 0 0 0 16 8 8 0 % I
% Lys: 0 8 0 8 0 0 0 16 0 0 8 0 0 0 0 % K
% Leu: 8 0 70 8 8 24 0 0 0 0 70 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 70 0 % M
% Asn: 0 0 0 0 62 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 8 0 8 0 0 8 0 70 0 0 70 % P
% Gln: 0 0 0 70 8 0 8 0 0 70 0 0 0 0 0 % Q
% Arg: 0 8 8 0 0 0 0 8 0 0 8 0 62 0 8 % R
% Ser: 0 0 8 0 0 8 0 62 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 0 0 8 0 0 0 0 0 8 0 8 % T
% Val: 77 0 0 0 0 70 0 8 8 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 0 0 0 0 8 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _