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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT2A All Species: 39.7
Human Site: Y645 Identified Species: 72.78
UniProt: Q92830 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92830 NP_066564.2 837 93926 Y645 Y L G Y I K D Y E G A T L M E
Chimpanzee Pan troglodytes XP_511500 837 93951 Y645 Y L G Y I K D Y E G A T L M E
Rhesus Macaque Macaca mulatta XP_001086807 858 97361 Y666 Y V G Y I K D Y E G A T L M G
Dog Lupus familis XP_548094 837 93980 Y645 Y L G Y I K D Y E G A T L M E
Cat Felis silvestris
Mouse Mus musculus Q9JHD2 830 93373 Y638 Y L G Y I K D Y E G A T L M E
Rat Rattus norvegicus NP_001100520 832 93633 Y640 Y L G Y I K D Y E G A T L M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515022 677 76679 I507 P Y T E L S H I I K K Q K E I
Chicken Gallus gallus NP_989660 804 91104 Y612 Y L G Y I K D Y E G A T L M E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922732 795 90605 Y603 Y L G Y I K D Y E G A T L M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648586 813 92151 Y616 Y A G Y I K E Y D S A T L M H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784879 808 92092 Y616 Y A G Y I K D Y E G A T L M G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9AR19 568 63105 S398 D E R I R E L S N C Q N V Y P
Baker's Yeast Sacchar. cerevisiae Q03330 439 51051 L269 D A G K I L L L Q E A A L R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 67.3 98.4 N.A. 97 97.9 N.A. 71.8 85.4 N.A. 81.1 N.A. 45.8 N.A. N.A. 59.1
Protein Similarity: 100 99.5 77.2 98.9 N.A. 97.7 98.3 N.A. 75.3 90.5 N.A. 86 N.A. 64.6 N.A. N.A. 74.9
P-Site Identity: 100 100 86.6 100 N.A. 100 100 N.A. 0 100 N.A. 100 N.A. 66.6 N.A. N.A. 86.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 6.6 100 N.A. 100 N.A. 80 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 28.6 26 N.A.
Protein Similarity: N.A. N.A. N.A. 45.5 36.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 0 0 0 0 0 0 0 85 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 0 70 0 8 0 0 0 0 0 0 % D
% Glu: 0 8 0 8 0 8 8 0 70 8 0 0 0 8 54 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 85 0 0 0 0 0 0 70 0 0 0 0 16 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 8 85 0 0 8 8 0 0 0 0 0 8 % I
% Lys: 0 0 0 8 0 77 0 0 0 8 8 0 8 0 0 % K
% Leu: 0 54 0 0 8 8 16 8 0 0 0 0 85 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 77 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 8 8 0 0 0 % Q
% Arg: 0 0 8 0 8 0 0 0 0 0 0 0 0 8 8 % R
% Ser: 0 0 0 0 0 8 0 8 0 8 0 0 0 0 0 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 0 77 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 77 8 0 77 0 0 0 77 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _