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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA4D
All Species:
18.18
Human Site:
Y759
Identified Species:
40
UniProt:
Q92854
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92854
NP_001135759.1
862
96150
Y759
F
Y
N
C
Y
K
G
Y
L
P
R
Q
C
L
K
Chimpanzee
Pan troglodytes
XP_001141771
928
103764
Y825
F
Y
N
C
Y
K
G
Y
L
P
R
Q
C
L
K
Rhesus Macaque
Macaca mulatta
XP_001090890
862
96305
Y759
F
Y
N
C
Y
K
G
Y
L
P
R
Q
C
L
K
Dog
Lupus familis
XP_533551
923
102696
Y818
S
Y
N
C
Y
K
G
Y
L
P
G
H
C
L
K
Cat
Felis silvestris
Mouse
Mus musculus
O09126
861
95696
Y758
S
Y
N
C
Y
K
G
Y
L
P
G
Q
C
L
K
Rat
Rattus norvegicus
Q9Z143
776
84280
V676
L
V
G
F
L
L
G
V
L
A
A
S
L
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509589
934
104195
N798
S
I
E
D
I
Y
R
N
M
C
S
N
N
N
V
Chicken
Gallus gallus
Q90665
295
33506
Q195
K
R
D
V
K
Y
T
Q
I
V
V
D
R
V
R
Frog
Xenopus laevis
NP_001131042
834
93072
Y733
L
W
D
P
S
S
F
Y
Y
S
D
G
S
L
K
Zebra Danio
Brachydanio rerio
Q9YHX4
766
85599
V666
K
E
K
E
R
T
L
V
A
M
V
V
I
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
R736
Y
N
T
Q
Q
S
Y
R
G
R
D
N
F
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
98.9
74.3
N.A.
85.6
31
N.A.
33.8
26.7
34.6
36.7
N.A.
26.4
N.A.
N.A.
N.A.
Protein Similarity:
100
92.6
99
83.2
N.A.
92.2
48.2
N.A.
51
30.9
50.7
53.1
N.A.
45.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
86.6
13.3
N.A.
0
0
20
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
86.6
13.3
N.A.
6.6
26.6
33.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% A
% Cys:
0
0
0
46
0
0
0
0
0
10
0
0
46
0
0
% C
% Asp:
0
0
19
10
0
0
0
0
0
0
19
10
0
0
0
% D
% Glu:
0
10
10
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
28
0
0
10
0
0
10
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
10
0
0
0
55
0
10
0
19
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
10
0
0
0
10
0
0
% I
% Lys:
19
0
10
0
10
46
0
0
0
0
0
0
0
0
55
% K
% Leu:
19
0
0
0
10
10
10
0
55
0
0
0
10
64
10
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
10
46
0
0
0
0
10
0
0
0
19
10
10
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
46
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
0
0
10
0
0
0
37
0
0
0
% Q
% Arg:
0
10
0
0
10
0
10
10
0
10
28
0
10
0
10
% R
% Ser:
28
0
0
0
10
19
0
0
0
10
10
10
10
0
10
% S
% Thr:
0
0
10
0
0
10
10
0
0
0
0
0
0
10
10
% T
% Val:
0
10
0
10
0
0
0
19
0
10
19
10
0
10
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
46
0
0
46
19
10
55
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _