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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APBB2
All Species:
19.39
Human Site:
S146
Identified Species:
42.67
UniProt:
Q92870
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92870
NP_775098.2
758
83346
S146
E
P
H
P
Q
D
S
S
S
C
E
I
L
P
S
Chimpanzee
Pan troglodytes
XP_001146547
758
83385
S146
E
P
H
P
Q
D
S
S
S
C
E
I
L
P
S
Rhesus Macaque
Macaca mulatta
XP_001097537
761
83630
S149
E
P
H
P
Q
D
S
S
G
C
E
I
L
P
S
Dog
Lupus familis
XP_851058
758
83089
S146
E
P
H
P
C
D
S
S
G
S
E
I
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBR4
760
83182
S146
D
P
H
P
Q
E
S
S
G
C
E
I
L
P
S
Rat
Rattus norvegicus
P46933
711
77638
Y117
P
K
G
L
M
H
L
Y
S
E
L
E
L
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507097
616
68316
Q22
T
T
L
Q
K
R
S
Q
L
I
I
P
I
P
S
Chicken
Gallus gallus
XP_420735
740
81441
S132
Q
D
P
N
K
N
L
S
T
T
A
G
V
S
V
Frog
Xenopus laevis
NP_001087003
610
66956
Q16
V
G
G
A
P
S
E
Q
T
K
P
K
W
Y
K
Zebra Danio
Brachydanio rerio
XP_693392
869
95380
N247
V
H
S
D
F
D
A
N
N
E
L
V
D
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787988
848
93773
V145
D
E
K
A
P
K
R
V
K
T
D
D
G
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
94.5
N.A.
93.9
46.3
N.A.
63.9
86.2
39.8
58.4
N.A.
N.A.
N.A.
N.A.
30.1
Protein Similarity:
100
99.8
98.2
96.5
N.A.
96
62.2
N.A.
70.4
90.9
53.9
68.4
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
100
93.3
80
N.A.
80
13.3
N.A.
20
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
93.3
20
N.A.
33.3
40
6.6
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
10
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
37
0
0
0
10
0
% C
% Asp:
19
10
0
10
0
46
0
0
0
0
10
10
10
0
0
% D
% Glu:
37
10
0
0
0
10
10
0
0
19
46
10
0
10
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
19
0
0
0
0
0
28
0
0
10
10
0
0
% G
% His:
0
10
46
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
10
46
10
0
0
% I
% Lys:
0
10
10
0
19
10
0
0
10
10
0
10
0
0
10
% K
% Leu:
0
0
10
10
0
0
19
0
10
0
19
0
55
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
10
10
0
0
0
0
0
0
% N
% Pro:
10
46
10
46
19
0
0
0
0
0
10
10
0
55
0
% P
% Gln:
10
0
0
10
37
0
0
19
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
10
55
55
28
10
0
0
0
19
64
% S
% Thr:
10
10
0
0
0
0
0
0
19
19
0
0
0
0
0
% T
% Val:
19
0
0
0
0
0
0
10
0
0
0
10
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _