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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APBB2
All Species:
16.36
Human Site:
S216
Identified Species:
36
UniProt:
Q92870
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92870
NP_775098.2
758
83346
S216
Q
K
P
N
R
P
Q
S
S
P
E
D
G
Q
V
Chimpanzee
Pan troglodytes
XP_001146547
758
83385
S216
Q
K
P
N
R
P
Q
S
S
P
E
D
G
Q
V
Rhesus Macaque
Macaca mulatta
XP_001097537
761
83630
S219
Q
K
P
S
K
P
Q
S
S
P
E
D
G
Q
V
Dog
Lupus familis
XP_851058
758
83089
F216
Q
K
A
N
K
A
Q
F
S
P
E
D
G
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBR4
760
83182
S216
Q
K
P
N
K
P
Q
S
S
P
E
D
G
Q
V
Rat
Rattus norvegicus
P46933
711
77638
E185
Q
G
L
P
E
P
L
E
N
V
E
V
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507097
616
68316
M90
D
P
S
P
G
A
V
M
P
K
Q
S
F
R
T
Chicken
Gallus gallus
XP_420735
740
81441
S200
D
K
S
A
Q
S
N
S
Q
A
S
T
I
I
V
Frog
Xenopus laevis
NP_001087003
610
66956
Q84
H
S
T
P
L
L
I
Q
P
P
N
G
D
E
E
Zebra Danio
Brachydanio rerio
XP_693392
869
95380
K327
T
K
P
L
L
E
N
K
K
D
P
C
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787988
848
93773
S232
T
P
F
D
S
G
P
S
T
M
D
D
E
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
94.5
N.A.
93.9
46.3
N.A.
63.9
86.2
39.8
58.4
N.A.
N.A.
N.A.
N.A.
30.1
Protein Similarity:
100
99.8
98.2
96.5
N.A.
96
62.2
N.A.
70.4
90.9
53.9
68.4
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
100
86.6
73.3
N.A.
93.3
20
N.A.
0
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
80
N.A.
100
26.6
N.A.
13.3
26.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
19
0
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
19
0
0
10
0
0
0
0
0
10
10
55
10
0
0
% D
% Glu:
0
0
0
0
10
10
0
10
0
0
55
0
10
10
10
% E
% Phe:
0
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
0
10
0
0
10
10
0
0
0
0
0
10
46
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% I
% Lys:
0
64
0
0
28
0
0
10
10
10
0
0
0
0
0
% K
% Leu:
0
0
10
10
19
10
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
37
0
0
19
0
10
0
10
0
0
0
0
% N
% Pro:
0
19
46
28
0
46
10
0
19
55
10
0
19
0
0
% P
% Gln:
55
0
0
0
10
0
46
10
10
0
10
0
0
46
0
% Q
% Arg:
0
0
0
0
19
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
19
10
10
10
0
55
46
0
10
10
0
19
10
% S
% Thr:
19
0
10
0
0
0
0
0
10
0
0
10
0
0
19
% T
% Val:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _