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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APBB2 All Species: 17.88
Human Site: S61 Identified Species: 39.33
UniProt: Q92870 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92870 NP_775098.2 758 83346 S61 K H T E T K N S T P P K C R K
Chimpanzee Pan troglodytes XP_001146547 758 83385 S61 K H T E T K N S T P P K C R K
Rhesus Macaque Macaca mulatta XP_001097537 761 83630 S64 K H T E T K N S T P P K C R K
Dog Lupus familis XP_851058 758 83089 S61 K H T E S K N S T P P K C R K
Cat Felis silvestris
Mouse Mus musculus Q9DBR4 760 83182 S61 K H S D A K N S T P P K C R K
Rat Rattus norvegicus P46933 711 77638 V46 K L Q A T A V V P K D L R S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507097 616 68316
Chicken Gallus gallus XP_420735 740 81441 E61 H N E L L N A E I R H T E T K
Frog Xenopus laevis NP_001087003 610 66956
Zebra Danio Brachydanio rerio XP_693392 869 95380 A139 D V I K Q G Q A T P P K C R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787988 848 93773 E62 S Q T D N K N E G E E E D E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98 94.5 N.A. 93.9 46.3 N.A. 63.9 86.2 39.8 58.4 N.A. N.A. N.A. N.A. 30.1
Protein Similarity: 100 99.8 98.2 96.5 N.A. 96 62.2 N.A. 70.4 90.9 53.9 68.4 N.A. N.A. N.A. N.A. 47.2
P-Site Identity: 100 100 100 93.3 N.A. 80 13.3 N.A. 0 6.6 0 46.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 93.3 13.3 N.A. 0 13.3 0 60 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 10 10 10 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 0 % C
% Asp: 10 0 0 19 0 0 0 0 0 0 10 0 10 0 10 % D
% Glu: 0 0 10 37 0 0 0 19 0 10 10 10 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % G
% His: 10 46 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 55 0 0 10 0 55 0 0 0 10 0 55 0 0 64 % K
% Leu: 0 10 0 10 10 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 10 55 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 55 55 0 0 0 0 % P
% Gln: 0 10 10 0 10 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 10 55 0 % R
% Ser: 10 0 10 0 10 0 0 46 0 0 0 0 0 10 0 % S
% Thr: 0 0 46 0 37 0 0 0 55 0 0 10 0 10 0 % T
% Val: 0 10 0 0 0 0 10 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _