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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APBB2 All Species: 26.06
Human Site: S728 Identified Species: 57.33
UniProt: Q92870 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92870 NP_775098.2 758 83346 S728 P P P P P A D S V T R R V T T
Chimpanzee Pan troglodytes XP_001146547 758 83385 S728 P P P P P A D S V T R R V T T
Rhesus Macaque Macaca mulatta XP_001097537 761 83630 S731 P P P P P A D S V T R R V T T
Dog Lupus familis XP_851058 758 83089 S728 P P P P P A D S V T R R V T T
Cat Felis silvestris
Mouse Mus musculus Q9DBR4 760 83182 S730 P P P P P A D S V T R R V T T
Rat Rattus norvegicus P46933 711 77638 V682 P A P P A E S V A R R V G W T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507097 616 68316 V587 P P P P E D S V T R R V T T N
Chicken Gallus gallus XP_420735 740 81441 S710 P P P P P A D S V T R R V T T
Frog Xenopus laevis NP_001087003 610 66956 V581 P T P P A D S V A R R V G S S
Zebra Danio Brachydanio rerio XP_693392 869 95380 S838 S Q A A P A D S V T R R V S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787988 848 93773 L795 T N S F N L L L R Y Q K C L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98 94.5 N.A. 93.9 46.3 N.A. 63.9 86.2 39.8 58.4 N.A. N.A. N.A. N.A. 30.1
Protein Similarity: 100 99.8 98.2 96.5 N.A. 96 62.2 N.A. 70.4 90.9 53.9 68.4 N.A. N.A. N.A. N.A. 47.2
P-Site Identity: 100 100 100 100 N.A. 100 33.3 N.A. 40 100 26.6 66.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 40 100 40 73.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 19 64 0 0 19 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 19 64 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 0 0 0 10 10 10 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 82 64 82 82 64 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 28 91 64 0 0 0 % R
% Ser: 10 0 10 0 0 0 28 64 0 0 0 0 0 19 10 % S
% Thr: 10 10 0 0 0 0 0 0 10 64 0 0 10 64 73 % T
% Val: 0 0 0 0 0 0 0 28 64 0 0 28 64 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _