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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMM1
All Species:
17.88
Human Site:
T146
Identified Species:
28.1
UniProt:
Q92871
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92871
NP_002667.2
262
29747
T146
S
P
I
G
R
S
C
T
L
E
E
R
I
E
F
Chimpanzee
Pan troglodytes
XP_001169480
244
27648
E131
G
R
S
C
T
L
E
E
R
I
E
F
S
E
L
Rhesus Macaque
Macaca mulatta
XP_001102327
246
28005
G133
M
L
N
V
S
P
I
G
R
S
C
S
Q
E
E
Dog
Lupus familis
XP_531715
253
28928
T137
S
P
I
G
R
S
C
T
L
E
E
R
I
E
F
Cat
Felis silvestris
Mouse
Mus musculus
O35621
262
29756
T146
S
P
I
G
R
S
C
T
L
E
E
R
I
E
F
Rat
Rattus norvegicus
NP_001008324
262
29670
T146
S
P
I
G
R
S
C
T
L
E
E
R
I
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521730
233
26488
R121
R
S
C
T
P
E
E
R
I
E
F
S
E
L
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088586
260
29809
T144
S
P
I
G
R
S
C
T
R
E
E
R
I
E
F
Zebra Danio
Brachydanio rerio
NP_956378
250
28394
G136
M
L
N
V
S
P
I
G
R
S
C
S
Q
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTZ6
254
29648
R140
M
N
V
C
P
I
G
R
Q
C
T
R
E
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUE6
245
28123
R131
I
N
L
S
P
I
G
R
S
C
S
Q
E
E
R
Sea Urchin
Strong. purpuratus
XP_793484
248
28280
R135
I
N
I
C
P
I
G
R
S
C
S
Y
P
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140792
249
28111
R137
I
N
V
S
P
I
G
R
N
C
S
Q
E
E
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80840
246
27743
G134
M
L
N
V
S
P
I
G
R
N
C
S
Q
E
E
Baker's Yeast
Sacchar. cerevisiae
P07283
254
29044
G140
M
I
N
V
S
P
I
G
R
N
A
S
T
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
65.2
88.9
N.A.
95
95
N.A.
79.7
N.A.
77
64.1
N.A.
52.2
N.A.
44.6
54.2
Protein Similarity:
100
93.1
77.4
92.3
N.A.
98
97.3
N.A.
84.7
N.A.
88.1
77.4
N.A.
67.9
N.A.
61.4
69.8
P-Site Identity:
100
13.3
6.6
100
N.A.
100
100
N.A.
6.6
N.A.
93.3
0
N.A.
13.3
N.A.
6.6
13.3
P-Site Similarity:
100
13.3
6.6
100
N.A.
100
100
N.A.
13.3
N.A.
93.3
6.6
N.A.
20
N.A.
20
13.3
Percent
Protein Identity:
N.A.
53.8
N.A.
53
53.8
N.A.
Protein Similarity:
N.A.
69.8
N.A.
68.3
66.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
7
20
0
0
34
0
0
27
20
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
7
14
7
0
40
40
0
27
87
27
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
34
% F
% Gly:
7
0
0
34
0
0
27
27
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
7
40
0
0
27
27
0
7
7
0
0
34
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
7
0
0
7
0
0
27
0
0
0
0
7
7
% L
% Met:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
27
27
0
0
0
0
0
7
14
0
0
0
0
0
% N
% Pro:
0
34
0
0
34
27
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
14
20
7
0
% Q
% Arg:
7
7
0
0
34
0
0
34
40
0
0
40
0
0
27
% R
% Ser:
34
7
7
14
27
34
0
0
14
14
20
34
7
0
0
% S
% Thr:
0
0
0
7
7
0
0
34
0
0
7
0
7
0
0
% T
% Val:
0
0
14
27
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _