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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNASE1L2
All Species:
8.79
Human Site:
S78
Identified Species:
21.48
UniProt:
Q92874
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92874
NP_001365.1
299
32853
S78
A
L
M
E
Q
I
N
S
V
S
E
H
E
Y
S
Chimpanzee
Pan troglodytes
XP_001168176
282
31357
N76
A
V
G
K
L
L
D
N
L
N
Q
D
A
P
D
Rhesus Macaque
Macaca mulatta
XP_001084351
253
28441
R49
V
T
G
R
P
R
R
R
G
V
G
R
V
S
E
Dog
Lupus familis
XP_547180
218
23407
L14
L
L
A
A
L
W
A
L
G
A
T
G
A
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1G0
278
31120
S70
D
P
D
L
S
A
V
S
L
L
M
E
Q
I
N
Rat
Rattus norvegicus
P21704
284
32046
R79
K
L
L
D
E
L
N
R
D
I
P
D
N
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506333
315
35674
I83
I
A
D
V
I
V
K
I
L
N
R
Y
D
I
A
Chicken
Gallus gallus
Q9YGI5
282
31382
S77
K
L
V
S
Q
L
N
S
A
S
S
Y
P
Y
S
Frog
Xenopus laevis
NP_001079750
295
34205
S74
L
L
M
A
Q
L
N
S
Q
S
E
T
R
N
Q
Zebra Danio
Brachydanio rerio
NP_001002674
278
30996
S73
A
T
S
K
L
M
D
S
V
N
G
G
S
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.8
70.2
61.8
N.A.
77.5
48.4
N.A.
46.3
51.8
44.1
45.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.5
73.5
65.5
N.A.
81.9
63.5
N.A.
60.9
65.8
57.8
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
6.6
N.A.
6.6
20
N.A.
0
46.6
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
0
20
N.A.
26.6
46.6
N.A.
40
66.6
53.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
10
10
20
0
10
10
0
10
10
0
0
20
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
20
10
0
0
20
0
10
0
0
20
10
0
10
% D
% Glu:
0
0
0
10
10
0
0
0
0
0
20
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
0
0
0
0
0
20
0
20
20
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
10
10
0
10
0
10
0
0
0
20
0
% I
% Lys:
20
0
0
20
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
20
50
10
10
30
40
0
10
30
10
0
0
0
0
0
% L
% Met:
0
0
20
0
0
10
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
40
10
0
30
0
0
10
10
10
% N
% Pro:
0
10
0
0
10
0
0
0
0
0
10
0
10
10
10
% P
% Gln:
0
0
0
0
30
0
0
0
10
0
10
0
10
0
10
% Q
% Arg:
0
0
0
10
0
10
10
20
0
0
10
10
10
0
10
% R
% Ser:
0
0
10
10
10
0
0
50
0
30
10
0
10
20
20
% S
% Thr:
0
20
0
0
0
0
0
0
0
0
10
10
0
0
0
% T
% Val:
10
10
10
10
0
10
10
0
20
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
20
0
30
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _