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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAD50
All Species:
25.76
Human Site:
S243
Identified Species:
43.59
UniProt:
Q92878
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92878
NP_005723.2
1312
153892
S243
S
S
K
E
I
V
K
S
Y
E
N
E
L
D
P
Chimpanzee
Pan troglodytes
Q7YR37
807
91634
Rhesus Macaque
Macaca mulatta
XP_001099384
1312
153869
S243
S
S
K
E
I
V
K
S
Y
E
N
E
L
D
P
Dog
Lupus familis
XP_531901
1312
153838
S243
S
S
K
E
I
V
K
S
Y
E
N
E
L
D
P
Cat
Felis silvestris
Mouse
Mus musculus
P70388
1312
153469
S243
S
S
Q
E
I
V
R
S
Y
E
D
E
L
E
P
Rat
Rattus norvegicus
Q9JIL8
1312
153765
A243
S
S
R
E
I
V
K
A
Y
E
N
E
L
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508900
1355
157237
T243
S
S
K
D
I
V
K
T
Y
E
N
D
L
D
P
Chicken
Gallus gallus
XP_414645
1314
153291
S244
A
S
K
E
N
I
K
S
I
E
S
Q
L
D
P
Frog
Xenopus laevis
NP_001154855
1312
153677
S243
V
S
K
E
N
V
K
S
I
E
S
Q
L
E
P
Zebra Danio
Brachydanio rerio
XP_696859
1332
155840
R243
S
S
K
E
S
V
N
R
I
E
G
Q
I
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W252
1318
152113
E250
A
I
K
A
Q
C
S
E
C
E
E
E
M
K
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44199
1298
150378
E242
K
R
K
E
E
T
D
E
L
K
E
R
K
A
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL02
1316
152796
E244
S
S
K
V
Q
M
L
E
L
E
T
S
V
Q
K
Baker's Yeast
Sacchar. cerevisiae
P12753
1312
152550
E242
Q
Y
N
E
E
V
S
E
I
E
S
Q
L
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20
99.3
96.1
N.A.
92.2
92
N.A.
78.2
76.3
74.6
69.8
N.A.
29.5
N.A.
26.4
N.A.
Protein Similarity:
100
35
99.9
98.4
N.A.
97.4
97.2
N.A.
87
89.6
88.1
84.9
N.A.
53.5
N.A.
49.5
N.A.
P-Site Identity:
100
0
100
100
N.A.
73.3
80
N.A.
80
60
60
53.3
N.A.
26.6
N.A.
13.3
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
100
86.6
80
66.6
N.A.
40
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.7
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
8
8
0
43
0
% D
% Glu:
0
0
0
72
15
0
0
29
0
86
15
43
0
22
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
43
8
0
0
29
0
0
0
8
0
0
% I
% Lys:
8
0
72
0
0
0
50
0
0
8
0
0
8
8
8
% K
% Leu:
0
0
0
0
0
0
8
0
15
0
0
0
65
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
15
0
8
0
0
0
36
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
72
% P
% Gln:
8
0
8
0
15
0
0
0
0
0
0
29
0
8
0
% Q
% Arg:
0
8
8
0
0
0
8
8
0
0
0
8
0
0
0
% R
% Ser:
58
72
0
0
8
0
15
43
0
0
22
8
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% T
% Val:
8
0
0
8
0
65
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
43
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _