Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAD50 All Species: 37.88
Human Site: S471 Identified Species: 64.1
UniProt: Q92878 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92878 NP_005723.2 1312 153892 S471 L Q Q L E G S S D R I L E L D
Chimpanzee Pan troglodytes Q7YR37 807 91634 K76 Q Q V Q Q K K K R D T R K G R
Rhesus Macaque Macaca mulatta XP_001099384 1312 153869 S471 L Q Q L E G S S D R I L E L D
Dog Lupus familis XP_531901 1312 153838 S471 L Q Q L E G S S D R I L E L D
Cat Felis silvestris
Mouse Mus musculus P70388 1312 153469 S471 L Q Q L E G S S D R I L E L D
Rat Rattus norvegicus Q9JIL8 1312 153765 S471 L Q Q L E G S S D R I L E L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508900 1355 157237 S471 L Q Q L E G S S D R I L E L D
Chicken Gallus gallus XP_414645 1314 153291 S472 L C Q L E G S S D R I A E L D
Frog Xenopus laevis NP_001154855 1312 153677 S471 L Q Q L E G S S D R L Q E L D
Zebra Danio Brachydanio rerio XP_696859 1332 155840 S471 L Q K L E G S S N R L Q E L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W252 1318 152113 M478 I K K I E T S M Q D L K K L E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44199 1298 150378 T458 I K Q G Q N A T A G M K D L L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL02 1316 152796 R528 I K T L N R E R D V M A G D A
Baker's Yeast Sacchar. cerevisiae P12753 1312 152550 Q518 E N Q I E K F Q D R I M K T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20 99.3 96.1 N.A. 92.2 92 N.A. 78.2 76.3 74.6 69.8 N.A. 29.5 N.A. 26.4 N.A.
Protein Similarity: 100 35 99.9 98.4 N.A. 97.4 97.2 N.A. 87 89.6 88.1 84.9 N.A. 53.5 N.A. 49.5 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 100 86.6 86.6 73.3 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 86.6 93.3 93.3 N.A. 66.6 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.8 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 53.7 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 8 0 0 15 0 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 72 15 0 0 8 8 65 % D
% Glu: 8 0 0 0 79 0 8 0 0 0 0 0 65 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 65 0 0 0 8 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 22 0 0 15 0 0 0 0 0 0 58 0 0 0 0 % I
% Lys: 0 22 15 0 0 15 8 8 0 0 0 15 22 0 0 % K
% Leu: 65 0 0 72 0 0 0 0 0 0 22 43 0 79 8 % L
% Met: 0 0 0 0 0 0 0 8 0 0 15 8 0 0 0 % M
% Asn: 0 8 0 0 8 8 0 0 8 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 65 72 8 15 0 0 8 8 0 0 15 0 0 0 % Q
% Arg: 0 0 0 0 0 8 0 8 8 72 0 8 0 0 8 % R
% Ser: 0 0 0 0 0 0 72 65 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 0 8 0 8 0 0 8 0 0 8 0 % T
% Val: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _