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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAD50
All Species:
30.3
Human Site:
S584
Identified Species:
51.28
UniProt:
Q92878
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92878
NP_005723.2
1312
153892
S584
E
D
W
L
H
S
K
S
K
E
I
N
Q
T
R
Chimpanzee
Pan troglodytes
Q7YR37
807
91634
K186
K
E
E
K
S
K
G
K
A
K
P
Q
N
K
F
Rhesus Macaque
Macaca mulatta
XP_001099384
1312
153869
S584
E
D
W
L
H
S
K
S
K
E
I
N
Q
T
R
Dog
Lupus familis
XP_531901
1312
153838
S584
E
D
W
L
H
S
K
S
K
E
I
N
Q
T
R
Cat
Felis silvestris
Mouse
Mus musculus
P70388
1312
153469
S584
E
D
W
L
H
S
K
S
K
E
I
N
Q
T
R
Rat
Rattus norvegicus
Q9JIL8
1312
153765
S584
E
D
W
L
H
S
K
S
K
E
I
N
Q
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508900
1355
157237
T584
E
D
W
L
H
C
K
T
K
E
I
N
Q
T
R
Chicken
Gallus gallus
XP_414645
1314
153291
S585
E
D
W
L
H
G
K
S
T
E
I
N
E
T
R
Frog
Xenopus laevis
NP_001154855
1312
153677
R584
E
D
W
L
Y
S
K
R
K
D
I
N
Q
T
R
Zebra Danio
Brachydanio rerio
XP_696859
1332
155840
S584
E
D
W
I
Y
S
K
S
R
E
I
K
S
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W252
1318
152113
E591
R
S
M
Q
V
V
Y
E
K
L
R
R
E
I
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44199
1298
150378
K572
F
H
K
L
R
N
D
K
K
I
M
E
E
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL02
1316
152796
L641
K
R
Y
I
E
S
K
L
Q
A
L
K
Q
E
S
Baker's Yeast
Sacchar. cerevisiae
P12753
1312
152550
I630
Q
K
S
K
E
K
V
I
Q
L
L
S
E
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20
99.3
96.1
N.A.
92.2
92
N.A.
78.2
76.3
74.6
69.8
N.A.
29.5
N.A.
26.4
N.A.
Protein Similarity:
100
35
99.9
98.4
N.A.
97.4
97.2
N.A.
87
89.6
88.1
84.9
N.A.
53.5
N.A.
49.5
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
86.6
80
80
66.6
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
93.3
86.6
93.3
86.6
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.7
52.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
65
0
0
0
0
8
0
0
8
0
0
0
8
0
% D
% Glu:
65
8
8
0
15
0
0
8
0
58
0
8
29
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
50
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
8
0
8
65
0
0
8
0
% I
% Lys:
15
8
8
15
0
15
72
15
65
8
0
15
0
8
0
% K
% Leu:
0
0
0
65
0
0
0
8
0
15
15
0
0
0
15
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
58
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
0
15
0
0
8
58
0
8
% Q
% Arg:
8
8
0
0
8
0
0
8
8
0
8
8
0
0
65
% R
% Ser:
0
8
8
0
8
58
0
50
0
0
0
8
8
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
0
0
0
65
0
% T
% Val:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
15
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _