Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAD50 All Species: 30.91
Human Site: Y1081 Identified Species: 52.31
UniProt: Q92878 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92878 NP_005723.2 1312 153892 Y1081 A L G R Q K G Y E E E I I H F
Chimpanzee Pan troglodytes Q7YR37 807 91634 V586 P P P L S P P V L G L H G V T
Rhesus Macaque Macaca mulatta XP_001099384 1312 153869 Y1081 A L G R Q K G Y E E E I I H F
Dog Lupus familis XP_531901 1312 153838 Y1081 A I G R Q K G Y E E E I I H F
Cat Felis silvestris
Mouse Mus musculus P70388 1312 153469 Y1081 A L G R Q K G Y E D E I L H F
Rat Rattus norvegicus Q9JIL8 1312 153765 Y1081 A L G R Q K G Y E E E I L H F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508900 1355 157237 Y1081 A L G R Q K G Y E E E I I H F
Chicken Gallus gallus XP_414645 1314 153291 F1083 A L G R Q R G F E E E I V R F
Frog Xenopus laevis NP_001154855 1312 153677 F1081 A L G R Q K G F E D E I L R F
Zebra Danio Brachydanio rerio XP_696859 1332 155840 Y1081 A L G R Q K G Y E D E I L R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W252 1318 152113 I1088 L L G Q L G E I H S Q V N K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44199 1298 150378 Y1055 I Y T Q M Q E Y E K Q K K I A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL02 1316 152796 V1068 N I G G I A A V E A E I V K I
Baker's Yeast Sacchar. cerevisiae P12753 1312 152550 Y1060 A E A E R D K Y Q E E S L R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20 99.3 96.1 N.A. 92.2 92 N.A. 78.2 76.3 74.6 69.8 N.A. 29.5 N.A. 26.4 N.A.
Protein Similarity: 100 35 99.9 98.4 N.A. 97.4 97.2 N.A. 87 89.6 88.1 84.9 N.A. 53.5 N.A. 49.5 N.A.
P-Site Identity: 100 0 100 93.3 N.A. 86.6 93.3 N.A. 100 73.3 73.3 80 N.A. 13.3 N.A. 13.3 N.A.
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 100 93.3 93.3 93.3 N.A. 33.3 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.8 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 53.7 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 72 0 8 0 0 8 8 0 0 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 22 0 0 0 0 0 % D
% Glu: 0 8 0 8 0 0 15 0 79 50 79 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 65 % F
% Gly: 0 0 79 8 0 8 65 0 0 8 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 43 0 % H
% Ile: 8 15 0 0 8 0 0 8 0 0 0 72 29 8 8 % I
% Lys: 0 0 0 0 0 58 8 0 0 8 0 8 8 15 0 % K
% Leu: 8 65 0 8 8 0 0 0 8 0 8 0 36 0 15 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 8 8 8 0 0 8 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 15 65 8 0 0 8 0 15 0 0 0 0 % Q
% Arg: 0 0 0 65 8 8 0 0 0 0 0 0 0 29 0 % R
% Ser: 0 0 0 0 8 0 0 0 0 8 0 8 0 0 0 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 0 0 0 0 0 0 0 15 0 0 0 8 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 65 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _