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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAD50 All Species: 38.18
Human Site: Y1124 Identified Species: 64.62
UniProt: Q92878 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92878 NP_005723.2 1312 153892 Y1124 V N K D L D I Y Y K T L D Q A
Chimpanzee Pan troglodytes Q7YR37 807 91634 P621 S R I C I V G P N G V G K S T
Rhesus Macaque Macaca mulatta XP_001099384 1312 153869 Y1124 V N K D L D I Y Y K T L D Q A
Dog Lupus familis XP_531901 1312 153838 Y1124 V N K D L D I Y Y K T L D Q A
Cat Felis silvestris
Mouse Mus musculus P70388 1312 153469 Y1124 V N K D L D I Y Y K T L D Q A
Rat Rattus norvegicus Q9JIL8 1312 153765 Y1124 V N K D L D I Y Y K T L D H A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508900 1355 157237 Y1124 V N K D L D I Y Y K T L D Q A
Chicken Gallus gallus XP_414645 1314 153291 Y1126 V N K D L D I Y Y K A L D K A
Frog Xenopus laevis NP_001154855 1312 153677 Y1124 A I K D L D I Y Y K T L D Q A
Zebra Danio Brachydanio rerio XP_696859 1332 155840 Y1124 A N K D L D I Y Y K A L D Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W252 1318 152113 Y1131 C I E D L G Q Y R L A L E W A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44199 1298 150378 Y1098 S I S D L T K Y R N C L D A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL02 1316 152796 L1107 I S K N R V E L K Q A Q Y K D
Baker's Yeast Sacchar. cerevisiae P12753 1312 152550 Q1098 Q I D S L T H Q L R T D Y K D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20 99.3 96.1 N.A. 92.2 92 N.A. 78.2 76.3 74.6 69.8 N.A. 29.5 N.A. 26.4 N.A.
Protein Similarity: 100 35 99.9 98.4 N.A. 97.4 97.2 N.A. 87 89.6 88.1 84.9 N.A. 53.5 N.A. 49.5 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 93.3 N.A. 100 86.6 86.6 80 N.A. 33.3 N.A. 33.3 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 93.3 N.A. 100 93.3 86.6 80 N.A. 46.6 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.8 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 53.7 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 0 0 0 0 29 0 0 8 65 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 8 79 0 65 0 0 0 0 0 8 72 0 15 % D
% Glu: 0 0 8 0 0 0 8 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 8 0 0 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % H
% Ile: 8 29 8 0 8 0 65 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 72 0 0 0 8 0 8 65 0 0 8 22 0 % K
% Leu: 0 0 0 0 86 0 0 8 8 8 0 79 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 58 0 8 0 0 0 0 8 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 8 8 0 8 0 8 0 50 0 % Q
% Arg: 0 8 0 0 8 0 0 0 15 8 0 0 0 0 0 % R
% Ser: 15 8 8 8 0 0 0 0 0 0 0 0 0 8 8 % S
% Thr: 0 0 0 0 0 15 0 0 0 0 58 0 0 0 15 % T
% Val: 50 0 0 0 0 15 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 79 65 0 0 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _