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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAD50 All Species: 7.88
Human Site: Y206 Identified Species: 13.33
UniProt: Q92878 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92878 NP_005723.2 1312 153892 Y206 Q G Q K V K E Y Q M E L K Y L
Chimpanzee Pan troglodytes Q7YR37 807 91634
Rhesus Macaque Macaca mulatta XP_001099384 1312 153869 Y206 Q G Q K V K E Y Q M E L K Y L
Dog Lupus familis XP_531901 1312 153838 C206 Q G Q K V K E C Q T E L K Y L
Cat Felis silvestris
Mouse Mus musculus P70388 1312 153469 C206 Q G Q K V K E C Q T E L K Y L
Rat Rattus norvegicus Q9JIL8 1312 153765 C206 Q G Q K V K E C Q T E L K Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508900 1355 157237 C206 Q S G R V K E C Q T E L K Y L
Chicken Gallus gallus XP_414645 1314 153291 C207 Q G T K V K E C Q T E L K Y L
Frog Xenopus laevis NP_001154855 1312 153677 Y206 Q A H N V R E Y Q V E I K N L
Zebra Danio Brachydanio rerio XP_696859 1332 155840 C206 Q T N T V K S C Q M E L K Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W252 1318 152113 K213 A M E E L K I K E A N I K H V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44199 1298 150378 H205 F K K E M Q T H E M S K Q L Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL02 1316 152796 F207 Q A Q E I K T F K L K L E N L
Baker's Yeast Sacchar. cerevisiae P12753 1312 152550 L205 M S V D I K L L K Q S V E H L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20 99.3 96.1 N.A. 92.2 92 N.A. 78.2 76.3 74.6 69.8 N.A. 29.5 N.A. 26.4 N.A.
Protein Similarity: 100 35 99.9 98.4 N.A. 97.4 97.2 N.A. 87 89.6 88.1 84.9 N.A. 53.5 N.A. 49.5 N.A.
P-Site Identity: 100 0 100 86.6 N.A. 86.6 86.6 N.A. 66.6 80 53.3 66.6 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 0 100 86.6 N.A. 86.6 86.6 N.A. 73.3 80 73.3 66.6 N.A. 60 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.8 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 53.7 52.1 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 0 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 22 0 0 58 0 15 0 65 0 15 0 0 % E
% Phe: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 43 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 8 0 0 0 0 0 15 0 % H
% Ile: 0 0 0 0 15 0 8 0 0 0 0 15 0 0 0 % I
% Lys: 0 8 8 43 0 79 0 8 15 0 8 8 72 0 0 % K
% Leu: 0 0 0 0 8 0 8 8 0 8 0 65 0 8 79 % L
% Met: 8 8 0 0 8 0 0 0 0 29 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 0 0 8 0 0 15 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 72 0 43 0 0 8 0 0 65 8 0 0 8 0 0 % Q
% Arg: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 15 0 0 0 0 8 0 0 0 15 0 0 0 0 % S
% Thr: 0 8 8 8 0 0 15 0 0 36 0 0 0 0 0 % T
% Val: 0 0 8 0 65 0 0 0 0 8 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 22 0 0 0 0 0 58 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _