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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC2 All Species: 28.18
Human Site: S1001 Identified Species: 56.36
UniProt: Q92887 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92887 NP_000383.1 1545 174191 S1001 I G S N L W L S A W T S D S K
Chimpanzee Pan troglodytes XP_507976 1545 174118 S1001 I G S N L W L S A W T S D S K
Rhesus Macaque Macaca mulatta NP_001028019 1544 174170 S1001 I G S N L W L S A W T S D S K
Dog Lupus familis XP_548204 1523 168842 S989 I G A N V W L S A W T N E A M
Cat Felis silvestris
Mouse Mus musculus Q8VI47 1543 173681 S999 I G T N L W L S A W T S D S E
Rat Rattus norvegicus Q63120 1541 173365 S997 I G S N L W L S A W T S D S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519322 1419 159039 E905 K H D S S E G E I T V D V G A
Chicken Gallus gallus Q5F364 1525 170953 S991 L A S N Y W L S L W T D D P V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956883 1567 175626 S1019 I G Q N L W L S D W T D D S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 F776 I M N L S S S F L L F N I A K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 L937 R V S S S T W L S E W T D S G
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 E977 V W L K H W S E V N S R Y G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 95.4 46 N.A. 77.6 77.6 N.A. 60.8 47.5 N.A. 57.2 N.A. 29.9 N.A. N.A. N.A.
Protein Similarity: 100 99.7 97.6 65.6 N.A. 89.4 88.6 N.A. 73.6 67.5 N.A. 73.7 N.A. 48.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 60 N.A. 86.6 93.3 N.A. 0 53.3 N.A. 73.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 6.6 60 N.A. 73.3 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.5 38.5 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 57.4 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 0 0 0 50 0 0 0 0 17 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 9 0 0 25 67 0 9 % D
% Glu: 0 0 0 0 0 9 0 17 0 9 0 0 9 0 9 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % F
% Gly: 0 59 0 0 0 0 9 0 0 0 0 0 0 17 9 % G
% His: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 67 0 0 0 0 0 0 0 9 0 0 0 9 0 9 % I
% Lys: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 34 % K
% Leu: 9 0 9 9 50 0 67 9 17 9 0 0 0 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 9 67 0 0 0 0 0 9 0 17 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 0 0 50 17 25 9 17 67 9 0 9 42 0 59 9 % S
% Thr: 0 0 9 0 0 9 0 0 0 9 67 9 0 0 0 % T
% Val: 9 9 0 0 9 0 0 0 9 0 9 0 9 0 9 % V
% Trp: 0 9 0 0 0 75 9 0 0 67 9 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _