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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC2 All Species: 20
Human Site: S1007 Identified Species: 40
UniProt: Q92887 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92887 NP_000383.1 1545 174191 S1007 L S A W T S D S K I F N S T D
Chimpanzee Pan troglodytes XP_507976 1545 174118 S1007 L S A W T S D S K I F N S T D
Rhesus Macaque Macaca mulatta NP_001028019 1544 174170 S1007 L S A W T S D S K I F N S T D
Dog Lupus familis XP_548204 1523 168842 A995 L S A W T N E A M T E S Q Q N
Cat Felis silvestris
Mouse Mus musculus Q8VI47 1543 173681 S1005 L S A W T S D S E K Q N G T D
Rat Rattus norvegicus Q63120 1541 173365 S1003 L S A W T S D S D N L N G T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519322 1419 159039 G911 G E I T V D V G A N S E E E D
Chicken Gallus gallus Q5F364 1525 170953 P997 L S L W T D D P V V N G T Q Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956883 1567 175626 S1025 L S D W T D D S I E Y F N Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 A782 S F L L F N I A K K A S I R L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 S943 W L S E W T D S G T P K T H G
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 G983 S E V N S R Y G S N P N A A R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 95.4 46 N.A. 77.6 77.6 N.A. 60.8 47.5 N.A. 57.2 N.A. 29.9 N.A. N.A. N.A.
Protein Similarity: 100 99.7 97.6 65.6 N.A. 89.4 88.6 N.A. 73.6 67.5 N.A. 73.7 N.A. 48.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 33.3 N.A. 73.3 66.6 N.A. 6.6 33.3 N.A. 40 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 80 73.3 N.A. 6.6 46.6 N.A. 53.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.5 38.5 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 57.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 0 0 0 0 17 9 0 9 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 25 67 0 9 0 0 0 0 0 42 % D
% Glu: 0 17 0 9 0 0 9 0 9 9 9 9 9 9 0 % E
% Phe: 0 9 0 0 9 0 0 0 0 0 25 9 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 17 9 0 0 9 17 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 9 0 0 0 9 0 9 25 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 34 17 0 9 0 0 0 % K
% Leu: 67 9 17 9 0 0 0 0 0 0 9 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 17 0 0 0 25 9 50 9 0 17 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 17 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 9 25 9 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 9 % R
% Ser: 17 67 9 0 9 42 0 59 9 0 9 17 25 0 0 % S
% Thr: 0 0 0 9 67 9 0 0 0 17 0 0 17 42 9 % T
% Val: 0 0 9 0 9 0 9 0 9 9 0 0 0 0 0 % V
% Trp: 9 0 0 67 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _