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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC2 All Species: 16.36
Human Site: S926 Identified Species: 32.73
UniProt: Q92887 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92887 NP_000383.1 1545 174191 S926 S N G R H L K S L R N S L K T
Chimpanzee Pan troglodytes XP_507976 1545 174118 S926 S S G R H L K S L R N S L K T
Rhesus Macaque Macaca mulatta NP_001028019 1544 174170 S926 S S S R H L K S L K N S L K T
Dog Lupus familis XP_548204 1523 168842 G911 V M S S E G E G Q G W P V P R
Cat Felis silvestris
Mouse Mus musculus Q8VI47 1543 173681 S924 S G S R R G K S L K S S L K I
Rat Rattus norvegicus Q63120 1541 173365 S922 S S S R R G K S L K N S L K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519322 1419 159039 K836 V G K H I F N K V L G P N G L
Chicken Gallus gallus Q5F364 1525 170953 S920 Y S R E T G K S Q H Q S S T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956883 1567 175626 G945 Q R H S K R N G S V K V R K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 L707 Y F Q A G G G L V A F L V M L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8G9 1622 181908 N868 P V E N G N A N N L Q K D G I
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 R906 S D A I S L R R A S D A T L G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 95.4 46 N.A. 77.6 77.6 N.A. 60.8 47.5 N.A. 57.2 N.A. 29.9 N.A. N.A. N.A.
Protein Similarity: 100 99.7 97.6 65.6 N.A. 89.4 88.6 N.A. 73.6 67.5 N.A. 73.7 N.A. 48.2 N.A. N.A. N.A.
P-Site Identity: 100 93.3 80 0 N.A. 53.3 60 N.A. 0 20 N.A. 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 13.3 N.A. 66.6 73.3 N.A. 6.6 26.6 N.A. 6.6 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.5 38.5 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 57.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 9 0 9 9 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 9 0 9 0 0 % D
% Glu: 0 0 9 9 9 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 9 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 17 17 0 17 42 9 17 0 9 9 0 0 17 9 % G
% His: 0 0 9 9 25 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 25 % I
% Lys: 0 0 9 0 9 0 50 9 0 25 9 9 0 50 0 % K
% Leu: 0 0 0 0 0 34 0 9 42 17 0 9 42 9 17 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 9 0 9 0 9 17 9 9 0 34 0 9 0 9 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 17 0 9 0 % P
% Gln: 9 0 9 0 0 0 0 0 17 0 17 0 0 0 0 % Q
% Arg: 0 9 9 42 17 9 9 9 0 17 0 0 9 0 9 % R
% Ser: 50 34 34 17 9 0 0 50 9 9 9 50 9 0 0 % S
% Thr: 0 0 0 0 9 0 0 0 0 0 0 0 9 9 25 % T
% Val: 17 9 0 0 0 0 0 0 17 9 0 9 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _