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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC2
All Species:
18.18
Human Site:
T406
Identified Species:
36.36
UniProt:
Q92887
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92887
NP_000383.1
1545
174191
T406
S
V
Y
K
K
A
L
T
L
S
N
L
A
R
K
Chimpanzee
Pan troglodytes
XP_507976
1545
174118
T406
S
V
Y
K
K
A
L
T
L
S
N
L
A
R
K
Rhesus Macaque
Macaca mulatta
NP_001028019
1544
174170
T406
S
V
Y
K
K
A
L
T
L
S
N
L
A
R
K
Dog
Lupus familis
XP_548204
1523
168842
V390
V
I
Y
R
K
A
L
V
I
T
N
S
A
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI47
1543
173681
T404
S
V
Y
K
K
A
L
T
L
S
N
L
A
R
R
Rat
Rattus norvegicus
Q63120
1541
173365
T402
S
I
Y
K
K
A
L
T
L
S
N
L
A
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519322
1419
159039
D367
F
V
I
K
L
V
H
D
L
L
A
F
V
S
P
Chicken
Gallus gallus
Q5F364
1525
170953
V408
V
I
Y
R
K
A
L
V
I
T
N
S
A
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956883
1567
175626
V425
A
V
Y
K
K
A
L
V
V
S
N
D
S
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
P238
L
F
M
L
L
F
M
P
I
Q
M
Y
L
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8G9
1622
181908
R385
A
V
F
R
K
S
L
R
L
T
N
E
G
R
K
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
V391
L
I
Y
Q
K
S
L
V
L
S
N
E
A
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.4
46
N.A.
77.6
77.6
N.A.
60.8
47.5
N.A.
57.2
N.A.
29.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.6
65.6
N.A.
89.4
88.6
N.A.
73.6
67.5
N.A.
73.7
N.A.
48.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
40
N.A.
93.3
93.3
N.A.
20
53.3
N.A.
66.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
20
80
N.A.
86.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
38.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
57.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
67
0
0
0
0
9
0
67
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% E
% Phe:
9
9
9
0
0
9
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
9
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
9
0
0
0
0
0
25
0
0
0
0
0
0
% I
% Lys:
0
0
0
59
84
0
0
0
0
0
0
0
0
9
59
% K
% Leu:
17
0
0
9
17
0
84
0
67
9
0
42
9
0
0
% L
% Met:
0
0
9
0
0
0
9
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
25
0
0
0
9
0
0
0
0
0
67
17
% R
% Ser:
42
0
0
0
0
17
0
0
0
59
0
17
9
17
0
% S
% Thr:
0
0
0
0
0
0
0
42
0
25
0
0
0
0
9
% T
% Val:
17
59
0
0
0
9
0
34
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
75
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _