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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC4
All Species:
30.91
Human Site:
S312
Identified Species:
56.67
UniProt:
Q92889
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92889
NP_005227.1
916
104486
S312
T
F
L
N
L
L
E
S
L
R
A
T
E
K
A
Chimpanzee
Pan troglodytes
XP_510831
916
104478
S312
T
F
L
N
L
L
E
S
L
R
A
T
E
K
A
Rhesus Macaque
Macaca mulatta
XP_001107209
916
104412
S312
T
F
L
N
L
L
E
S
L
R
A
T
E
K
A
Dog
Lupus familis
XP_536967
917
104078
S313
T
F
L
N
L
L
E
S
L
R
A
T
E
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD4
917
103672
S312
T
F
L
N
L
L
E
S
L
R
A
T
E
K
V
Rat
Rattus norvegicus
XP_222534
917
103888
S312
T
F
L
N
L
L
E
S
L
R
A
T
E
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505617
688
78099
S98
F
L
T
N
R
I
P
S
D
L
I
T
G
I
L
Chicken
Gallus gallus
XP_414734
904
103087
S301
T
F
L
N
L
L
E
S
L
K
A
S
E
K
A
Frog
Xenopus laevis
NP_001086576
897
102089
N297
Y
D
C
V
T
F
L
N
L
L
E
S
M
K
A
Zebra Danio
Brachydanio rerio
NP_956079
886
101028
Q290
T
L
L
L
Y
L
T
Q
Y
D
C
V
T
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24087
961
109500
A333
H
D
A
V
S
A
Y
A
F
M
K
R
Y
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKI5
956
107616
T301
S
F
L
K
F
L
D
T
L
R
V
S
E
S
Y
Baker's Yeast
Sacchar. cerevisiae
P06777
1100
126352
L422
D
F
F
G
E
I
Q
L
S
L
D
A
N
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
90.8
N.A.
86
86.8
N.A.
55.7
68.8
73.4
62.9
N.A.
39.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
94.9
N.A.
92.3
92.8
N.A.
64.5
78.4
85.1
78.2
N.A.
60
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
86.6
20
20
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
100
33.3
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.3
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
8
0
0
54
8
0
0
47
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
16
0
0
0
0
8
0
8
8
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
54
0
0
0
8
0
62
0
0
% E
% Phe:
8
70
8
0
8
8
0
0
8
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
8
0
0
70
0
% K
% Leu:
0
16
70
8
54
70
8
8
70
24
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
62
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
54
0
8
0
8
0
% R
% Ser:
8
0
0
0
8
0
0
62
8
0
0
24
0
8
8
% S
% Thr:
62
0
8
0
8
0
8
8
0
0
0
54
8
0
0
% T
% Val:
0
0
0
16
0
0
0
0
0
0
8
8
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
8
0
8
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _