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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC4
All Species:
17.88
Human Site:
S465
Identified Species:
32.78
UniProt:
Q92889
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92889
NP_005227.1
916
104486
S465
S
S
K
R
I
R
K
S
H
K
R
P
K
D
P
Chimpanzee
Pan troglodytes
XP_510831
916
104478
P465
S
S
K
R
I
R
K
P
H
K
R
P
K
D
P
Rhesus Macaque
Macaca mulatta
XP_001107209
916
104412
S465
S
S
K
R
I
R
K
S
H
K
R
P
K
D
P
Dog
Lupus familis
XP_536967
917
104078
S466
S
P
K
R
M
A
R
S
N
K
R
P
K
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD4
917
103672
S465
G
P
K
R
T
T
K
S
D
K
R
P
K
A
A
Rat
Rattus norvegicus
XP_222534
917
103888
S465
G
P
K
R
T
M
K
S
D
K
R
P
K
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505617
688
78099
G251
D
P
L
W
H
Q
L
G
A
K
T
K
S
L
V
Chicken
Gallus gallus
XP_414734
904
103087
P454
K
S
K
G
N
A
R
P
D
T
G
P
Q
A
K
Frog
Xenopus laevis
NP_001086576
897
102089
S450
K
A
K
G
N
N
K
S
M
K
T
S
I
H
K
Zebra Danio
Brachydanio rerio
NP_956079
886
101028
Q443
L
K
L
D
K
G
W
Q
K
K
D
S
A
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24087
961
109500
G486
G
S
Q
P
P
L
A
G
M
D
E
L
A
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKI5
956
107616
S454
E
W
E
M
Y
L
L
S
K
I
E
L
R
S
M
Baker's Yeast
Sacchar. cerevisiae
P06777
1100
126352
T575
V
T
T
K
R
R
R
T
R
G
A
S
Q
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
90.8
N.A.
86
86.8
N.A.
55.7
68.8
73.4
62.9
N.A.
39.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
94.9
N.A.
92.3
92.8
N.A.
64.5
78.4
85.1
78.2
N.A.
60
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
66.6
N.A.
53.3
60
N.A.
6.6
20
26.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
86.6
N.A.
53.3
60
N.A.
13.3
33.3
33.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.3
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
16
8
0
8
0
8
0
16
16
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
24
8
8
0
0
39
0
% D
% Glu:
8
0
8
0
0
0
0
0
0
0
16
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
24
0
0
16
0
8
0
16
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
24
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
24
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
16
8
62
8
8
0
47
0
16
70
0
8
47
0
16
% K
% Leu:
8
0
16
0
0
16
16
0
0
0
0
16
0
8
8
% L
% Met:
0
0
0
8
8
8
0
0
16
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
16
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
31
0
8
8
0
0
16
0
0
0
54
0
0
31
% P
% Gln:
0
0
8
0
0
8
0
8
0
0
0
0
16
8
0
% Q
% Arg:
0
0
0
47
8
31
24
0
8
0
47
0
8
8
0
% R
% Ser:
31
39
0
0
0
0
0
54
0
0
0
24
8
8
8
% S
% Thr:
0
8
8
0
16
8
0
8
0
8
16
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _