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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC4
All Species:
30.3
Human Site:
S683
Identified Species:
55.56
UniProt:
Q92889
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92889
NP_005227.1
916
104486
S683
E
Q
N
G
T
Q
Q
S
I
V
V
D
M
R
E
Chimpanzee
Pan troglodytes
XP_510831
916
104478
S683
E
Q
N
G
T
Q
Q
S
I
V
V
D
M
R
E
Rhesus Macaque
Macaca mulatta
XP_001107209
916
104412
S683
E
Q
N
G
T
Q
Q
S
V
V
V
D
M
R
E
Dog
Lupus familis
XP_536967
917
104078
T684
E
Q
N
R
T
Q
Q
T
I
V
V
D
V
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD4
917
103672
S684
E
Q
N
G
T
Q
S
S
I
V
V
D
M
R
E
Rat
Rattus norvegicus
XP_222534
917
103888
S684
E
R
N
G
T
Q
P
S
I
V
V
D
M
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505617
688
78099
T462
Q
T
K
T
Q
D
L
T
L
T
Q
M
L
E
K
Chicken
Gallus gallus
XP_414734
904
103087
T670
A
Q
K
T
A
Q
Q
T
I
I
V
D
M
R
E
Frog
Xenopus laevis
NP_001086576
897
102089
T664
V
Q
N
N
V
Q
Q
T
I
I
V
D
M
R
E
Zebra Danio
Brachydanio rerio
NP_956079
886
101028
R654
E
E
V
K
E
P
H
R
I
I
V
D
M
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24087
961
109500
K697
Q
A
T
K
E
T
P
K
V
I
V
D
M
R
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKI5
956
107616
Q725
K
E
L
E
K
E
T
Q
V
I
V
D
M
R
E
Baker's Yeast
Sacchar. cerevisiae
P06777
1100
126352
V821
F
H
N
L
T
Q
D
V
V
I
V
D
T
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
90.8
N.A.
86
86.8
N.A.
55.7
68.8
73.4
62.9
N.A.
39.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
94.9
N.A.
92.3
92.8
N.A.
64.5
78.4
85.1
78.2
N.A.
60
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
93.3
86.6
N.A.
0
60
66.6
46.6
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
33.3
73.3
80
60
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.3
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
0
93
0
0
0
% D
% Glu:
54
16
0
8
16
8
0
0
0
0
0
0
0
8
93
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
62
47
0
0
0
0
0
% I
% Lys:
8
0
16
16
8
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
0
0
8
8
0
0
8
0
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
77
0
0
% M
% Asn:
0
0
62
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
16
0
0
0
0
0
0
0
0
% P
% Gln:
16
54
0
0
8
70
47
8
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
0
0
0
93
0
% R
% Ser:
0
0
0
0
0
0
8
39
0
0
0
0
0
0
0
% S
% Thr:
0
8
8
16
54
8
8
31
0
8
0
0
8
0
0
% T
% Val:
8
0
8
0
8
0
0
8
31
47
93
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _