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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC4
All Species:
31.52
Human Site:
T439
Identified Species:
57.78
UniProt:
Q92889
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92889
NP_005227.1
916
104486
T439
L
L
R
L
Y
R
K
T
F
E
K
D
S
K
A
Chimpanzee
Pan troglodytes
XP_510831
916
104478
T439
L
L
R
L
Y
R
K
T
F
E
K
D
S
K
A
Rhesus Macaque
Macaca mulatta
XP_001107209
916
104412
T439
L
L
R
L
Y
R
K
T
F
E
K
D
S
K
A
Dog
Lupus familis
XP_536967
917
104078
T440
L
M
R
L
Y
R
K
T
F
E
K
D
S
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD4
917
103672
T439
L
L
R
L
Y
R
K
T
F
E
K
D
G
K
A
Rat
Rattus norvegicus
XP_222534
917
103888
T439
L
L
R
L
Y
R
K
T
F
E
K
D
G
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505617
688
78099
L225
P
S
L
E
V
E
D
L
T
L
E
N
A
I
G
Chicken
Gallus gallus
XP_414734
904
103087
T428
L
M
R
L
Y
N
K
T
L
G
K
D
E
K
A
Frog
Xenopus laevis
NP_001086576
897
102089
T424
L
M
R
L
Y
N
K
T
F
G
R
D
E
K
A
Zebra Danio
Brachydanio rerio
NP_956079
886
101028
L417
I
Q
K
G
P
E
H
L
L
N
R
L
Y
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24087
961
109500
S460
A
K
E
S
Q
T
R
S
A
P
P
K
N
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKI5
956
107616
S428
V
A
C
K
D
E
R
S
C
M
Q
L
E
D
C
Baker's Yeast
Sacchar. cerevisiae
P06777
1100
126352
D549
V
K
E
V
Q
S
Q
D
T
F
P
E
N
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
90.8
N.A.
86
86.8
N.A.
55.7
68.8
73.4
62.9
N.A.
39.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
94.9
N.A.
92.3
92.8
N.A.
64.5
78.4
85.1
78.2
N.A.
60
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
66.6
66.6
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
73.3
80
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.3
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
8
0
0
0
8
8
62
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
8
0
8
8
0
0
0
62
0
8
0
% D
% Glu:
0
0
16
8
0
24
0
0
0
47
8
8
24
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
54
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
16
0
0
16
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
16
8
8
0
0
62
0
0
0
54
8
0
62
0
% K
% Leu:
62
39
8
62
0
0
0
16
16
8
0
16
0
0
0
% L
% Met:
0
24
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
16
0
0
0
8
0
8
16
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
0
8
16
0
0
0
0
% P
% Gln:
0
8
0
0
16
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
62
0
0
47
16
0
0
0
16
0
0
0
8
% R
% Ser:
0
8
0
8
0
8
0
16
0
0
0
0
31
8
8
% S
% Thr:
0
0
0
0
0
8
0
62
16
0
0
0
0
0
8
% T
% Val:
16
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
62
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _