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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC4
All Species:
13.64
Human Site:
T493
Identified Species:
25
UniProt:
Q92889
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92889
NP_005227.1
916
104486
T493
K
K
K
K
R
K
L
T
L
T
Q
M
V
G
K
Chimpanzee
Pan troglodytes
XP_510831
916
104478
T493
K
K
K
K
R
K
L
T
L
T
Q
M
V
G
K
Rhesus Macaque
Macaca mulatta
XP_001107209
916
104412
T493
K
K
K
K
R
K
L
T
L
T
Q
M
V
G
K
Dog
Lupus familis
XP_536967
917
104078
T494
K
K
K
K
R
R
L
T
L
T
Q
M
V
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD4
917
103672
L493
L
K
R
K
K
Q
E
L
T
L
T
Q
V
L
G
Rat
Rattus norvegicus
XP_222534
917
103888
L493
K
R
K
K
K
R
E
L
T
L
T
Q
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505617
688
78099
F279
S
Q
Y
D
C
V
T
F
L
N
L
L
E
S
L
Chicken
Gallus gallus
XP_414734
904
103087
V482
K
K
Q
H
D
Q
T
V
V
Q
M
I
G
K
T
Frog
Xenopus laevis
NP_001086576
897
102089
Q478
K
T
E
L
T
L
T
Q
M
I
G
K
G
E
E
Zebra Danio
Brachydanio rerio
NP_956079
886
101028
E471
S
K
K
P
A
K
M
E
K
L
S
R
V
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24087
961
109500
Q514
S
Y
M
L
T
M
T
Q
P
V
E
V
G
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKI5
956
107616
V482
F
G
I
L
D
G
V
V
P
V
T
T
I
Q
N
Baker's Yeast
Sacchar. cerevisiae
P06777
1100
126352
H603
M
E
V
V
F
E
D
H
K
L
S
E
E
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
90.8
N.A.
86
86.8
N.A.
55.7
68.8
73.4
62.9
N.A.
39.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
94.9
N.A.
92.3
92.8
N.A.
64.5
78.4
85.1
78.2
N.A.
60
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
20
26.6
N.A.
6.6
13.3
6.6
26.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
46.6
N.A.
20
40
26.6
40
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.3
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
16
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
0
0
8
16
8
0
0
8
8
16
8
8
% E
% Phe:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
8
0
24
31
16
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
8
0
8
8
8
0
% I
% Lys:
54
54
47
47
16
31
0
0
16
0
0
8
0
8
39
% K
% Leu:
8
0
0
24
0
8
31
16
39
31
8
8
0
16
8
% L
% Met:
8
0
8
0
0
8
8
0
8
0
8
31
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
0
0
0
16
0
0
0
0
8
0
% P
% Gln:
0
8
8
0
0
16
0
16
0
8
31
16
0
8
8
% Q
% Arg:
0
8
8
0
31
16
0
0
0
0
0
8
0
0
0
% R
% Ser:
24
0
0
0
0
0
0
0
0
0
16
0
0
16
0
% S
% Thr:
0
8
0
0
16
0
31
31
16
31
24
8
0
0
8
% T
% Val:
0
0
8
8
0
8
8
16
8
16
0
8
54
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _