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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC4
All Species:
24.85
Human Site:
Y344
Identified Species:
45.56
UniProt:
Q92889
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92889
NP_005227.1
916
104486
Y344
I
N
A
R
A
R
V
Y
H
L
P
D
A
K
M
Chimpanzee
Pan troglodytes
XP_510831
916
104478
Y344
I
N
A
R
A
R
V
Y
H
L
P
D
A
K
M
Rhesus Macaque
Macaca mulatta
XP_001107209
916
104412
Y344
I
N
A
R
A
R
V
Y
H
L
P
D
A
K
M
Dog
Lupus familis
XP_536967
917
104078
Y345
V
N
A
R
A
R
V
Y
H
L
P
D
A
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD4
917
103672
Y344
V
N
A
R
A
R
V
Y
R
V
P
D
V
K
L
Rat
Rattus norvegicus
XP_222534
917
103888
Y344
V
N
A
R
A
R
V
Y
R
V
P
D
V
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505617
688
78099
K130
R
L
F
R
Q
K
N
K
H
G
F
I
K
A
F
Chicken
Gallus gallus
XP_414734
904
103087
Y333
V
N
A
R
A
R
V
Y
R
T
A
D
E
K
L
Frog
Xenopus laevis
NP_001086576
897
102089
R329
T
S
M
F
V
H
A
R
A
R
V
F
H
V
P
Zebra Danio
Brachydanio rerio
NP_956079
886
101028
S322
G
W
L
F
L
D
S
S
M
S
M
F
V
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24087
961
109500
Q365
Q
I
F
K
L
S
R
Q
R
V
F
N
G
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKI5
956
107616
V333
K
K
R
V
Y
R
L
V
K
A
S
D
V
K
S
Baker's Yeast
Sacchar. cerevisiae
P06777
1100
126352
K454
Q
L
V
I
S
Y
A
K
K
R
I
F
Y
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
90.8
N.A.
86
86.8
N.A.
55.7
68.8
73.4
62.9
N.A.
39.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
94.9
N.A.
92.3
92.8
N.A.
64.5
78.4
85.1
78.2
N.A.
60
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
13.3
60
0
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
20
73.3
6.6
0
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.3
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
54
0
54
0
16
0
8
8
8
0
31
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
62
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
16
16
0
0
0
0
0
0
16
24
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
39
0
0
0
8
0
0
% H
% Ile:
24
8
0
8
0
0
0
0
0
0
8
8
0
0
0
% I
% Lys:
8
8
0
8
0
8
0
16
16
0
0
0
8
70
0
% K
% Leu:
0
16
8
0
16
0
8
0
0
31
0
0
0
0
24
% L
% Met:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
31
% M
% Asn:
0
54
0
0
0
0
8
0
0
0
0
8
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
8
% P
% Gln:
16
0
0
0
8
0
0
8
0
0
0
0
0
8
8
% Q
% Arg:
8
0
8
62
0
62
8
8
31
16
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
8
8
8
0
8
8
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
31
0
8
8
8
0
54
8
0
24
8
0
31
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
54
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _