KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC4
All Species:
13.94
Human Site:
Y514
Identified Species:
25.56
UniProt:
Q92889
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92889
NP_005227.1
916
104486
Y514
E
G
D
V
E
E
G
Y
R
R
E
I
S
S
S
Chimpanzee
Pan troglodytes
XP_510831
916
104478
Y514
E
G
D
V
E
E
G
Y
R
R
E
I
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001107209
916
104412
Y514
E
G
D
V
E
E
G
Y
C
R
E
I
S
S
S
Dog
Lupus familis
XP_536967
917
104078
Y515
E
Q
D
V
K
E
G
Y
P
R
D
T
G
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD4
917
103672
L515
D
K
A
L
E
E
D
L
C
R
Q
T
S
S
S
Rat
Rattus norvegicus
XP_222534
917
103888
L515
E
G
A
V
E
E
D
L
H
K
Q
T
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505617
688
78099
N296
T
E
K
T
F
G
Q
N
S
G
W
L
F
L
D
Chicken
Gallus gallus
XP_414734
904
103087
D501
R
E
E
L
D
V
E
D
N
K
E
L
N
G
S
Frog
Xenopus laevis
NP_001086576
897
102089
T496
G
K
D
G
E
E
E
T
Y
G
E
E
S
M
S
Zebra Danio
Brachydanio rerio
NP_956079
886
101028
E488
S
A
D
K
D
L
N
E
N
S
E
D
E
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24087
961
109500
V531
D
I
K
P
D
P
D
V
S
I
F
E
T
I
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKI5
956
107616
K556
R
S
L
R
S
C
N
K
K
T
T
N
S
K
P
Baker's Yeast
Sacchar. cerevisiae
P06777
1100
126352
A648
I
L
I
D
D
G
D
A
E
F
D
N
G
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
90.8
N.A.
86
86.8
N.A.
55.7
68.8
73.4
62.9
N.A.
39.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
94.9
N.A.
92.3
92.8
N.A.
64.5
78.4
85.1
78.2
N.A.
60
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
40
46.6
N.A.
0
13.3
40
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
73.3
N.A.
60
60
N.A.
6.6
53.3
40
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.3
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
16
0
0
0
0
0
0
% C
% Asp:
16
0
47
8
31
0
31
8
0
0
16
8
0
0
8
% D
% Glu:
39
16
8
0
47
54
16
8
8
0
47
16
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
8
0
8
0
0
% F
% Gly:
8
31
0
8
0
16
31
0
0
16
0
0
24
16
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
0
0
0
8
0
24
0
8
0
% I
% Lys:
0
16
16
8
8
0
0
8
8
16
0
0
0
8
0
% K
% Leu:
0
8
8
16
0
8
0
16
0
0
0
16
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
16
8
16
0
0
16
8
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
16
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
16
0
0
0
0
% Q
% Arg:
16
0
0
8
0
0
0
0
16
39
0
0
0
0
0
% R
% Ser:
8
8
0
0
8
0
0
0
16
8
0
0
47
47
62
% S
% Thr:
8
0
0
8
0
0
0
8
0
8
8
24
8
0
0
% T
% Val:
0
0
0
39
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _