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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC4
All Species:
35.15
Human Site:
Y577
Identified Species:
64.44
UniProt:
Q92889
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92889
NP_005227.1
916
104486
Y577
L
H
E
V
E
P
R
Y
V
V
L
Y
D
A
E
Chimpanzee
Pan troglodytes
XP_510831
916
104478
Y577
L
H
E
V
E
P
R
Y
V
V
L
Y
D
A
E
Rhesus Macaque
Macaca mulatta
XP_001107209
916
104412
Y577
L
H
E
V
E
P
R
Y
V
V
L
Y
D
A
E
Dog
Lupus familis
XP_536967
917
104078
Y578
L
H
E
V
E
P
R
Y
V
V
L
Y
D
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD4
917
103672
Y578
L
H
E
V
E
P
R
Y
V
V
L
Y
D
A
E
Rat
Rattus norvegicus
XP_222534
917
103888
Y578
L
H
E
V
E
P
R
Y
V
V
L
Y
D
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505617
688
78099
E359
P
K
W
E
A
L
T
E
V
L
K
E
I
E
I
Chicken
Gallus gallus
XP_414734
904
103087
Y564
L
H
E
V
E
P
R
Y
V
V
L
Y
D
A
E
Frog
Xenopus laevis
NP_001086576
897
102089
Y559
L
H
E
I
E
P
R
Y
V
V
L
Y
D
S
E
Zebra Danio
Brachydanio rerio
NP_956079
886
101028
L551
V
D
P
M
F
V
V
L
Y
D
A
E
L
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24087
961
109500
A594
M
Y
N
M
N
V
T
A
I
R
Q
L
E
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKI5
956
107616
V619
L
D
I
L
K
P
S
V
I
I
V
Y
H
P
D
Baker's Yeast
Sacchar. cerevisiae
P06777
1100
126352
Y711
L
Q
E
M
M
P
S
Y
I
I
M
F
E
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.3
90.8
N.A.
86
86.8
N.A.
55.7
68.8
73.4
62.9
N.A.
39.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
94.9
N.A.
92.3
92.8
N.A.
64.5
78.4
85.1
78.2
N.A.
60
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
86.6
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
100
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.3
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
0
8
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
0
0
0
0
8
0
0
62
0
16
% D
% Glu:
0
0
70
8
62
0
0
8
0
0
0
16
16
8
62
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
16
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
62
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
24
16
0
0
8
0
8
% I
% Lys:
0
8
0
0
8
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
77
0
0
8
0
8
0
8
0
8
62
8
8
0
0
% L
% Met:
8
0
0
24
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
77
0
0
0
0
0
0
0
16
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
62
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
16
0
0
0
0
0
0
16
0
% S
% Thr:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
54
0
16
8
8
70
62
8
0
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
70
8
0
0
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _