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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UFD1L
All Species:
26.67
Human Site:
Y219
Identified Species:
53.33
UniProt:
Q92890
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92890
NP_005650.2
307
34500
Y219
G
E
A
D
H
S
G
Y
A
G
E
L
G
F
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104799
307
34424
Y219
G
E
A
G
H
S
G
Y
A
G
E
L
G
F
R
Dog
Lupus familis
XP_850373
499
55148
Y298
G
E
A
D
H
S
G
Y
A
G
E
M
G
F
R
Cat
Felis silvestris
Mouse
Mus musculus
P70362
307
34466
Y219
G
E
A
D
H
S
G
Y
A
G
E
V
G
F
R
Rat
Rattus norvegicus
Q9ES53
307
34467
Y219
G
E
A
D
H
S
G
Y
A
G
E
V
G
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989632
307
34544
Y219
V
E
A
D
H
S
G
Y
V
S
D
V
G
F
R
Frog
Xenopus laevis
NP_001083638
307
34839
Y219
N
E
P
D
H
S
E
Y
A
V
D
L
G
F
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTF9
316
34773
A224
E
I
A
G
A
T
N
A
I
L
E
E
V
V
E
Honey Bee
Apis mellifera
XP_396320
298
34112
P215
V
D
P
A
D
L
M
P
A
P
S
G
F
V
P
Nematode Worm
Caenorhab. elegans
Q19584
342
36886
R250
S
V
F
G
G
A
G
R
R
L
D
G
K
K
K
Sea Urchin
Strong. purpuratus
XP_784491
308
35058
Y219
D
N
T
D
Y
S
Q
Y
I
D
V
N
K
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53044
361
39792
G223
K
E
K
K
N
S
F
G
K
G
Q
V
L
D
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
51.9
N.A.
98.3
98.6
N.A.
N.A.
94.7
91.2
N.A.
N.A.
57.9
58.9
37.7
61.3
Protein Similarity:
100
N.A.
99.6
54.7
N.A.
99.3
99.3
N.A.
N.A.
98
95.4
N.A.
N.A.
69.3
73.2
53.7
73.7
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
66.6
N.A.
N.A.
13.3
6.6
6.6
33.3
P-Site Similarity:
100
N.A.
93.3
100
N.A.
100
100
N.A.
N.A.
80
73.3
N.A.
N.A.
20
13.3
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
59
9
9
9
0
9
59
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
59
9
0
0
0
0
9
25
0
0
9
0
% D
% Glu:
9
67
0
0
0
0
9
0
0
0
50
9
0
0
9
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
0
0
9
67
0
% F
% Gly:
42
0
0
25
9
0
59
9
0
50
0
17
59
0
0
% G
% His:
0
0
0
0
59
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
17
0
0
0
0
0
0
% I
% Lys:
9
0
9
9
0
0
0
0
9
0
0
0
17
9
9
% K
% Leu:
0
0
0
0
0
9
0
0
0
17
0
25
9
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% M
% Asn:
9
9
0
0
9
0
9
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
17
0
0
0
0
9
0
9
0
0
0
0
17
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
67
% R
% Ser:
9
0
0
0
0
75
0
0
0
9
9
0
0
0
0
% S
% Thr:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
17
9
0
0
0
0
0
0
9
9
9
34
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _