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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UPF1
All Species:
31.82
Human Site:
S218
Identified Species:
53.85
UniProt:
Q92900
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92900
NP_002902.2
1129
124345
S218
Q
P
C
A
S
Q
S
S
L
K
D
I
N
W
D
Chimpanzee
Pan troglodytes
XP_512972
974
107722
S152
C
N
G
R
G
N
T
S
G
S
H
I
V
N
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533868
1119
123129
S219
Q
P
C
A
S
Q
S
S
L
K
D
I
N
W
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU0
1124
123948
S213
Q
P
C
A
S
Q
S
S
L
K
D
I
N
W
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514946
1113
122992
S215
Q
P
C
A
S
Q
S
S
L
K
D
I
N
W
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Q98TR3
1097
122320
S200
Q
P
C
A
S
Q
S
S
L
K
D
I
N
W
D
Fruit Fly
Dros. melanogaster
Q9VYS3
1180
129895
S195
Q
P
C
A
A
Q
N
S
L
K
D
M
N
W
D
Honey Bee
Apis mellifera
XP_393330
1119
125484
S202
Q
P
C
A
A
Q
S
S
L
K
D
M
N
W
D
Nematode Worm
Caenorhab. elegans
O76512
1069
120001
F190
T
P
C
A
S
I
A
F
Q
N
D
D
N
W
S
Sea Urchin
Strong. purpuratus
XP_786803
1157
128015
N207
Q
P
C
A
T
Q
S
N
L
K
D
M
N
W
D
Poplar Tree
Populus trichocarpa
XP_002329539
1242
136050
A235
E
P
C
L
N
V
N
A
L
K
D
M
N
W
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJR0
1254
136850
A237
D
P
C
L
N
V
N
A
L
K
D
M
N
W
D
Baker's Yeast
Sacchar. cerevisiae
P30771
971
109412
R149
A
V
V
V
L
L
C
R
I
P
C
A
Q
T
K
Red Bread Mold
Neurospora crassa
Q9HEH1
1093
120070
S198
Q
P
C
G
A
S
T
S
T
K
D
M
S
W
D
Conservation
Percent
Protein Identity:
100
85.3
N.A.
98.7
N.A.
98.4
N.A.
N.A.
96.6
N.A.
N.A.
N.A.
86
62.4
70.2
47.6
71.5
Protein Similarity:
100
85.6
N.A.
98.9
N.A.
99.1
N.A.
N.A.
97.3
N.A.
N.A.
N.A.
89
73.7
80.5
62.6
81.3
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
100
80
86.6
46.6
80
P-Site Similarity:
100
20
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
100
100
100
53.3
100
Percent
Protein Identity:
55.7
N.A.
N.A.
55.2
45.4
52.7
Protein Similarity:
67.3
N.A.
N.A.
67.4
61.3
67.6
P-Site Identity:
53.3
N.A.
N.A.
53.3
0
53.3
P-Site Similarity:
86.6
N.A.
N.A.
80
6.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
65
22
0
8
15
0
0
0
8
0
0
0
% A
% Cys:
8
0
86
0
0
0
8
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
86
8
0
0
79
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
8
0
0
43
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
79
0
0
0
0
8
% K
% Leu:
0
0
0
15
8
8
0
0
72
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
43
0
0
0
% M
% Asn:
0
8
0
0
15
8
22
8
0
8
0
0
79
8
0
% N
% Pro:
0
86
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
65
0
0
0
0
58
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
43
8
50
65
0
8
0
0
8
0
8
% S
% Thr:
8
0
0
0
8
0
15
0
8
0
0
0
0
8
0
% T
% Val:
0
8
8
8
0
15
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _