Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPF1 All Species: 13.94
Human Site: S981 Identified Species: 23.59
UniProt: Q92900 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92900 NP_002902.2 1129 124345 S981 H D Q I G M I S A G P S H V A
Chimpanzee Pan troglodytes XP_512972 974 107722 F836 F Q G R E K D F I I L S C V R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533868 1119 123129 S971 H D Q I G M I S A G P S H V A
Cat Felis silvestris
Mouse Mus musculus Q9EPU0 1124 123948 S976 H D Q I S M I S A G P S H V A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514946 1113 122992 S967 H D Q I G M I S A G P S H V A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres Q98TR3 1097 122320 G949 H D Q I G M I G A A A S H L A
Fruit Fly Dros. melanogaster Q9VYS3 1180 129895 G950 S M N G G Q Y G G S G G G P Y
Honey Bee Apis mellifera XP_393330 1119 125484 L954 Y Y Q R N V P L D I F S R T H
Nematode Worm Caenorhab. elegans O76512 1069 120001 L927 N D P S Q P R L P P T Y S N S
Sea Urchin Strong. purpuratus XP_786803 1157 128015 Q957 N P G R V H D Q M G Y I Q P N
Poplar Tree Populus trichocarpa XP_002329539 1242 136050 H985 P G P P N G T H K P G V A G F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJR0 1254 136850 P990 G P P N G A R P G L H P A G Y
Baker's Yeast Sacchar. cerevisiae P30771 971 109412 C833 I H F R E K G C L V E G T L D
Red Bread Mold Neurospora crassa Q9HEH1 1093 120070 S955 D V S S I H S S A L G G A A L
Conservation
Percent
Protein Identity: 100 85.3 N.A. 98.7 N.A. 98.4 N.A. N.A. 96.6 N.A. N.A. N.A. 86 62.4 70.2 47.6 71.5
Protein Similarity: 100 85.6 N.A. 98.9 N.A. 99.1 N.A. N.A. 97.3 N.A. N.A. N.A. 89 73.7 80.5 62.6 81.3
P-Site Identity: 100 13.3 N.A. 100 N.A. 93.3 N.A. N.A. 100 N.A. N.A. N.A. 73.3 6.6 13.3 6.6 6.6
P-Site Similarity: 100 13.3 N.A. 100 N.A. 93.3 N.A. N.A. 100 N.A. N.A. N.A. 80 6.6 26.6 20 13.3
Percent
Protein Identity: 55.7 N.A. N.A. 55.2 45.4 52.7
Protein Similarity: 67.3 N.A. N.A. 67.4 61.3 67.6
P-Site Identity: 0 N.A. N.A. 6.6 0 13.3
P-Site Similarity: 0 N.A. N.A. 6.6 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 43 8 8 0 22 8 36 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % C
% Asp: 8 43 0 0 0 0 15 0 8 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 15 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 8 0 8 0 0 0 0 8 0 0 8 0 0 0 8 % F
% Gly: 8 8 15 8 43 8 8 15 15 36 22 22 8 15 0 % G
% His: 36 8 0 0 0 15 0 8 0 0 8 0 36 0 8 % H
% Ile: 8 0 0 36 8 0 36 0 8 15 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 15 0 0 8 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 15 8 15 8 0 0 15 8 % L
% Met: 0 8 0 0 0 36 0 0 8 0 0 0 0 0 0 % M
% Asn: 15 0 8 8 15 0 0 0 0 0 0 0 0 8 8 % N
% Pro: 8 15 22 8 0 8 8 8 8 15 29 8 0 15 0 % P
% Gln: 0 8 43 0 8 8 0 8 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 29 0 0 15 0 0 0 0 0 8 0 8 % R
% Ser: 8 0 8 15 8 0 8 36 0 8 0 50 8 0 8 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 8 0 8 8 0 % T
% Val: 0 8 0 0 8 8 0 0 0 8 0 8 0 36 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 8 0 0 0 8 8 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _