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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPF1 All Species: 13.64
Human Site: T1044 Identified Species: 23.08
UniProt: Q92900 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92900 NP_002902.2 1129 124345 T1044 G L P G P S Q T N L P N S Q A
Chimpanzee Pan troglodytes XP_512972 974 107722 N890 P L W N H L L N Y Y K E Q K V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533868 1119 123129 T1034 G L P G P S Q T N L P N S Q A
Cat Felis silvestris
Mouse Mus musculus Q9EPU0 1124 123948 T1039 G L P G P S Q T T L P N S Q A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514946 1113 122992 T1029 F G I P G P S T N I P N S Q A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres Q98TR3 1097 122320 S1012 F W E P G G W S H A K Q S D Q
Fruit Fly Dros. melanogaster Q9VYS3 1180 129895 S1069 G N F S P G N S G P G V T G V
Honey Bee Apis mellifera XP_393330 1119 125484 G1028 N K Q G P R M G K L S Q T E Q
Nematode Worm Caenorhab. elegans O76512 1069 120001 P982 G D Q R R P P P Q A E A A M D
Sea Urchin Strong. purpuratus XP_786803 1157 128015 L1063 Q N M S Q Y N L S L N S T Q N
Poplar Tree Populus trichocarpa XP_002329539 1242 136050 G1095 Q P G Y E F L G D D F K S Q G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJR0 1254 136850 A1109 G I S Q D F L A D D I K S Q G
Baker's Yeast Sacchar. cerevisiae P30771 971 109412 S887 F D A Q S M V S F S G Q I G D
Red Bread Mold Neurospora crassa Q9HEH1 1093 120070 N1009 I A G E S V A N S E F T D A T
Conservation
Percent
Protein Identity: 100 85.3 N.A. 98.7 N.A. 98.4 N.A. N.A. 96.6 N.A. N.A. N.A. 86 62.4 70.2 47.6 71.5
Protein Similarity: 100 85.6 N.A. 98.9 N.A. 99.1 N.A. N.A. 97.3 N.A. N.A. N.A. 89 73.7 80.5 62.6 81.3
P-Site Identity: 100 6.6 N.A. 100 N.A. 93.3 N.A. N.A. 46.6 N.A. N.A. N.A. 6.6 13.3 20 6.6 13.3
P-Site Similarity: 100 13.3 N.A. 100 N.A. 93.3 N.A. N.A. 53.3 N.A. N.A. N.A. 20 26.6 33.3 13.3 33.3
Percent
Protein Identity: 55.7 N.A. N.A. 55.2 45.4 52.7
Protein Similarity: 67.3 N.A. N.A. 67.4 61.3 67.6
P-Site Identity: 13.3 N.A. N.A. 20 0 0
P-Site Similarity: 20 N.A. N.A. 33.3 6.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 8 8 0 15 0 8 8 8 29 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 8 0 0 0 15 15 0 0 8 8 15 % D
% Glu: 0 0 8 8 8 0 0 0 0 8 8 8 0 8 0 % E
% Phe: 22 0 8 0 0 15 0 0 8 0 15 0 0 0 0 % F
% Gly: 43 8 15 29 15 15 0 15 8 0 15 0 0 15 15 % G
% His: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 0 0 0 0 0 8 8 0 8 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 8 0 15 15 0 8 0 % K
% Leu: 0 29 0 0 0 8 22 8 0 36 0 0 0 0 0 % L
% Met: 0 0 8 0 0 8 8 0 0 0 0 0 0 8 0 % M
% Asn: 8 15 0 8 0 0 15 15 22 0 8 29 0 0 8 % N
% Pro: 8 8 22 15 36 15 8 8 0 8 29 0 0 0 0 % P
% Gln: 15 0 15 15 8 0 22 0 8 0 0 22 8 50 15 % Q
% Arg: 0 0 0 8 8 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 15 15 22 8 22 15 8 8 8 50 0 0 % S
% Thr: 0 0 0 0 0 0 0 29 8 0 0 8 22 0 8 % T
% Val: 0 0 0 0 0 8 8 0 0 0 0 8 0 0 15 % V
% Trp: 0 8 8 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 8 0 0 8 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _