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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UPF1
All Species:
46.97
Human Site:
Y728
Identified Species:
79.49
UniProt:
Q92900
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92900
NP_002902.2
1129
124345
Y728
A
F
P
S
N
I
F
Y
E
G
S
L
Q
N
G
Chimpanzee
Pan troglodytes
XP_512972
974
107722
E603
R
A
L
K
R
T
A
E
R
E
L
L
M
N
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533868
1119
123129
Y718
A
F
P
S
N
I
F
Y
E
G
S
L
Q
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU0
1124
123948
Y723
A
F
P
S
N
I
F
Y
E
G
S
L
Q
N
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514946
1113
122992
Y714
A
F
P
S
N
I
F
Y
E
G
S
L
Q
N
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Q98TR3
1097
122320
Y698
A
F
P
S
N
I
F
Y
E
G
S
L
Q
N
G
Fruit Fly
Dros. melanogaster
Q9VYS3
1180
129895
Y698
Q
F
P
S
N
F
F
Y
E
G
S
L
Q
N
G
Honey Bee
Apis mellifera
XP_393330
1119
125484
Y701
R
F
P
S
N
F
F
Y
E
G
S
L
Q
N
G
Nematode Worm
Caenorhab. elegans
O76512
1069
120001
Y691
E
F
P
S
N
V
F
Y
D
G
S
L
Q
N
G
Sea Urchin
Strong. purpuratus
XP_786803
1157
128015
Y704
A
F
P
S
N
I
F
Y
E
G
S
L
Q
N
G
Poplar Tree
Populus trichocarpa
XP_002329539
1242
136050
Y732
E
F
P
S
N
N
F
Y
E
G
T
L
Q
N
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJR0
1254
136850
Y737
E
F
P
S
N
S
F
Y
E
G
T
L
Q
N
G
Baker's Yeast
Sacchar. cerevisiae
P30771
971
109412
Q600
V
I
L
V
G
D
H
Q
Q
L
G
P
V
I
L
Red Bread Mold
Neurospora crassa
Q9HEH1
1093
120070
Y702
E
F
P
S
N
M
F
Y
E
G
S
L
Q
N
G
Conservation
Percent
Protein Identity:
100
85.3
N.A.
98.7
N.A.
98.4
N.A.
N.A.
96.6
N.A.
N.A.
N.A.
86
62.4
70.2
47.6
71.5
Protein Similarity:
100
85.6
N.A.
98.9
N.A.
99.1
N.A.
N.A.
97.3
N.A.
N.A.
N.A.
89
73.7
80.5
62.6
81.3
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
100
86.6
86.6
80
100
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
100
86.6
86.6
93.3
100
Percent
Protein Identity:
55.7
N.A.
N.A.
55.2
45.4
52.7
Protein Similarity:
67.3
N.A.
N.A.
67.4
61.3
67.6
P-Site Identity:
80
N.A.
N.A.
80
0
86.6
P-Site Similarity:
86.6
N.A.
N.A.
86.6
6.6
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% D
% Glu:
29
0
0
0
0
0
0
8
79
8
0
0
0
0
0
% E
% Phe:
0
86
0
0
0
15
86
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
86
8
0
0
0
86
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
43
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
0
0
0
0
0
0
8
8
93
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
86
8
0
0
0
0
0
0
0
93
0
% N
% Pro:
0
0
86
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
8
8
0
0
0
86
0
0
% Q
% Arg:
15
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
86
0
8
0
0
0
0
72
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
15
0
0
0
0
% T
% Val:
8
0
0
8
0
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _